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Rabbit Anti-CADM4 Polyclonal Antibody#abs140617

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Description

Catalog-specification	Delivery time	USD price
abs140617-100ug	1-2 Weeks	301.0
abs140617-50ug	1-2 Weeks	201.0

Overview
catalog	abs140617
Other names	CADM4, also known as Nectin-like protein 4 or NECL4, is a member of the immunoglobulin superfamily that functions as a cell adhesion molecule. It is also referred to as TSLC1-like protein 2 or TSLL2, and is closely related to the TSLC1 protein. SynCAM4 is another name for CADM4. CADM4 is expressed in a variety of tissues, including the brain, heart, lungs, and kidney. It plays an important role in cell-cell adhesion, which is crucial for normal tissue development and maintenance. This protein is particularly important for the formation and maintenance of synapses between neurons in the brain. Recent studies have linked CADM4 to a number of diseases and conditions, including autism, schizophrenia, and cancer. Dysregulation of CADM4 expression has been observed in several different types of cancer, including lung, breast, and prostate cancer. Overall, CADM4 is a critical component of normal cell function, and its dysregulation can have profound effects on human health. Further research is needed to fully understand the role of this protein in normal physiology and disease.
Source	Rabbit
Specificity	Total CADM4 levels can be detected using the CADM4 Antibody, which specifically targets the endogenous CADM4.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Rabbit;Sheep;Dog;Horse;Bovine;
Antigen	CADM4
Application	The recommended dilution range for this antibody is 1:500 to 1:1000 for Western blotting, 1:50 to 1:200 for immunohistochemistry, and 1:100 to 1:500 for immunofluorescence or immunocytochemistry. For ELISA using peptide, the recommended dilution range is 1:20000 to 1:40000. It is important to follow the recommended dilution range in order to obtain optimal results.
Immunogen	A synthesized peptide.
MW	48 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed for peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage, it is recommended to keep at a temperature of -20 °C for up to one year. It is important to avoid exposing the product to repeated freeze/thaw cycles, as this can adversely affect its quality. Make sure to adhere to the storage guidelines to maintain the integrity of the product.
Storage buffer	This product contains Rabbit IgG suspended in a solution of phosphate buffered saline with a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol, making it ideal for long-term storage at a temperature of -20°C. You can expect this product to remain stable for up to 12 months from the date of purchase. Please note that this information is only intended as a guide, and you should always consult the product manual for detailed instructions.
Target
Background	Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.
Tissue specificity	Expressed in brain, prostate, brain, kidney and some other organs.
Posttranslational modification	N-glycosylated.
Celluar localization	Extracellular region or secreted;Plasma Membrane;
UniPort	Q8NFZ8