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Rabbit Anti-CABP4 Polyclonal Antibody#abs138828

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Description

Catalog-specification	Delivery time	USD price
abs138828-100ug	1-2 Weeks	301.0
abs138828-50ug	1-2 Weeks	201.0

Overview
catalog	abs138828
Other names	Human calcium binding protein 4, also known as CaBP4 or CABP4, plays a crucial role in calcium signaling. It is associated with a condition called Congenital Stationary Night Blindness 2B (CSNB2B). The protein, encoded by the CABP4 gene, binds to calcium ions and facilitates their transport within cells. This ability is vital for various physiological processes and the proper functioning of the visual system. By rearranging the given information, we understand that CABP4_HUMAN, also referred to as Calcium-binding protein 4, and CSNB 2B, are alternative names for CaBP4, which is involved in calcium signaling and is associated with a condition called Congenital Stationary Night Blindness 2B (CSNB2B).
Source	Rabbit
Specificity	The CABP4 Antibody is capable of detecting the complete levels of CABP4 present in the body naturally. This antibody detects the total endogenous CABP4 levels with high accuracy and specificity. By using this antibody, researchers can study the role of CABP4 in various biological processes and diseases. It is an effective tool for scientists who aim to investigate the function of CABP4 in the human body.
Species Reactivity	Human;Mouse
Predictive reaction species	Bovine;Pig;Sheep
Antigen	CABP4
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human CABP4.
MW	30kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. To achieve the highest level of similarity possible, the sentence structure has been rearranged while retaining the same core information.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for up to a year. To avoid any potential damage to the product, it is important to avoid any repeated freeze/thaw cycles during storage. Please note that this information is crucial to help ensure the product's effectiveness and longevity.
Storage buffer	This product is Rabbit IgG in phosphate buffered saline, with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20 °C and is expected to remain stable for up to 12 months from the date of receipt.
Target
Background	Involved in normal synaptic function through regulation of Ca2+ influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages (By similarity).
Tissue specificity	Expressed in retina and in the inner hair cells (IHC) of the cochlea.
Posttranslational modification	Phosphorylated. Phosphorylation levels change with the light conditions and regulate the activity (By similarity).
Celluar localization	Cytosol;Extracellular region or secreted;
UniPort	P57796