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Rabbit Anti-BNIP2 Polyclonal Antibody#abs140906

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Description

Catalog-specification	Delivery time	USD price
abs140906-100ug	1-2 Weeks	301.0
abs140906-50ug	1-2 Weeks	201.0

Overview
catalog	abs140906
Other names	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2, also known as BNIP2 or NIP2, plays a critical role in cell survival and apoptosis. It is a member of the BCL2 family, which regulates cell death by affecting mitochondrial function. BNIP2 interacts with BCL2 and the adenovirus E1B 19 kDa protein, which modulates cell cycle progression. The protein is also involved in autophagy, a process of self-digestion that is important for cellular homeostasis. BNIP2 is expressed in many tissues, including the brain, heart, and kidney, and mutations in the gene have been associated with developmental disorders such as Joubert syndrome and cortical malformations. Overall, BNIP2 is a critical mediator of cellular processes that are essential for growth, survival, and homeostasis.
Source	Rabbit
Specificity	The total level of endogenous BNIP2 can be detected with the BNIP2 Antibody. To create a similar content using the information from the original text, the following could be generated: If you want to determine the overall levels of BNIP2 that are present within a sample, the BNIP2 Antibody is the perfect solution. This antibody is specifically designed to detect total BNIP2 that is endogenous, meaning that it is produced naturally within the sample.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Zebrafish;Chicken;Rabbit;Xenopus;Dog;Horse;Bovine;Sheep;Pig
Antigen	BNIP2
Application	The dilution range for Western Blot (WB) is 1:500 to 1:1000, for Immunofluorescence/Immunocytochemistry (IF/ICC) is 1:100 to 1:500, and for Enzyme-Linked Immunosorbent Assay (ELISA) with peptide is 1:20000 to 1:40000. These dilutions are commonly used in molecular biology experiments for protein detection and quantification.
Immunogen	A synthesized peptide.
MW	36 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was carried out through peptide affinity chromatography. To ensure high quality and specificity of the produced antiserum, this technique was employed in the purification process.
Clonality	Polyclonal Antibody
Stability & Storage	It is advised to store it at -20 °C for a duration of one year to maintain its quality and effectiveness. To prevent any damage, it is important to avoid subjecting it to repeated freeze/thaw cycles.
Storage buffer	The storage conditions for Rabbit IgG are as follows: it should be kept in phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. The recommended storage temperature is -20 °C. It is important to note that this product remains stable for a period of 12 months from the date of receipt.
Target
Background	Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins.
Celluar localization	Cytosol;Nucleus;
UniPort	Q12982