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Rabbit Anti-PREX1 Polyclonal Antibody#abs139260

Please note that the price mentioned above is only for your reference. For detailed pricing information, kindly get in touch with our seller Vecent. Western blot analysis PREX1 using HuvEc whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in human.

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Description

Catalog-specification	Delivery time	USD price
abs139260-100ug	1-2 Weeks	301.0
abs139260-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. For detailed pricing information, kindly get in touch with our seller Vecent.

Overview
catalog	abs139260
Other names	Here are a few possible rewritten versions of the original text: 1. P-Rex1 is a protein that helps exchange Rac molecules, and it relies on the presence of phosphatidylinositol 3,4,5 trisphosphate to do so. It's also known as phosphatidylinositol 3,4,5 trisphosphate-dependent Rac exchanger 1, or PREX1. Another name for it is SET domain containing 6, or Setd6. It's also sometimes referred to as KIAA1415 or OTTHUMP00000031228. 2. The protein P-Rex1 is a critical element in the exchange of Rac molecules. Its activity depends on the presence of phosphatidylinositol 3,4,5 trisphosphate, which enables it to do its job. Other names for P-Rex1 include phosphatidylinositol 3,4,5 trisphosphate-dependent Rac exchange factor 1, or PRex1; and phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein. It's also known as KIAA1415, OTTHUMP00000031228, or SET domain containing 6 (Setd6). 3. An important player in the exchange of Rac molecules is P-Rex1, which relies on the activity of phosphatidylinositol 3,4,5 trisphosphate. This protein is also called phosphatidylinositol 3,4,5 trisphosphate-dependent Rac exchange factor 1 (or PRex1), and phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein. Other names for it include KIAA1415, OTTHUMP00000031228, and SET domain containing 6 (or Setd6).
Source	Rabbit
Specificity	The PREX1 Antibody is capable of detecting the overall levels of endogenous PREX1. This means that the antibody can identify the total PREX1 protein that is present in a sample, without missing any of its components. To rephrase this content, the detection ability of the PREX1 Antibody is such that it can effectively identify the complete presence of endogenous PREX1 levels.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Rabbit;Sheep;Dog;Bovine;Horse;
Antigen	PREX1
Application	The recommended dilution range for the use of this antibody in Western Blot is between 1:1000-3000, while for Immunohistochemistry the recommended dilution is 1:200. When it comes to ELISA using a peptide, the recommended dilution range is between 1:20000-1:40000. It is important to note that these dilution ranges are based on the original information provided.
Immunogen	A synthesized peptide derived from human PREX1.
MW	186 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. A highly identical content can be generated by rephrasing the original statement to convey the same information.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain optimal conditions, it is recommended to store the product at a temperature of -20 °C for a duration of one year. It is crucial to avoid subjecting it to repeated freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
Tissue specificity	Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues.
Celluar localization	Cytosol;Plasma Membrane;
UniPort	Q8TCU6