Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-BCLAF1 Polyclonal Antibody#abs140907

Description

Catalog-specification	Delivery time	USD price
abs140907-100ug	1-2 Weeks	301.0
abs140907-50ug	1-2 Weeks	201.0

Please note that the mentioned price is for your reference only. For detailed pricing information, kindly get in touch with our seller Vecent. It would be best if you could reach out to Vecent for further pricing details. The amount stated above is solely for your guidance, and Vecent can provide you with specific and accurate pricing information. So, please don't hesitate to contact Vecent to know more about our pricing.

Overview
catalog	abs140907
Other names	BCLAF1, also known as Bcl-2-associated transcription factor 1, is an important transcription factor that is associated with the Bcl-2 protein family. This factor is essential in regulating gene expression and plays a critical role in several biological processes. BCLAF1 is encoded by the KIAA0164 gene and is also referred to as BTF. Its function is to regulate the expression of genes involved in cell growth and differentiation, cell cycle progression, and apoptosis. The protein is composed of multiple domains and interacts with multiple proteins to control specific cellular processes. BCLAF1 is considered an essential player in the regulation of cellular senescence and has been implicated in several diseases, including cancer. Understanding the function of BCLAF1 is necessary for developing targeted therapies that can mitigate or treat various diseases.
Source	Rabbit
Specificity	The BCLAF1 Antibody is capable of detecting total BCLAF1 levels in the body. This means that the antibody has the ability to identify the amounts of BCLAF1 that already exist within the system.
Species Reactivity	Human;Mouse;Rat
Antigen	BCLAF1
Application	WB 1:500~1:1000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	106 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. To ensure a highly purified product, this process was utilized.
Clonality	Polyclonal Antibody
Stability & Storage	One recommendation for storing is to keep it at -20 °C for a duration of one year, making sure to prevent any freeze/thaw cycles from occurring. This approach will help maintain the stability and quality of the stored item.
Storage buffer	This rabbit IgG is stored in phosphate buffered saline with a pH of 7.4. It contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20 °C and is stable for 12 months from the date of receipt. Please note that the content generated by rearranging the original text information may vary significantly from the original text and may not provide the same level of accuracy.
Target
Background	The SNARP complex, a death-promoting transcriptional repressor, is potentially associated with cyclin-D1/CCND1 mRNA stability. This association involves the complex binding to both the 3' end of the CCND1 gene and its corresponding mRNA. It is postulated that the SNARP complex plays a role in regulating the expression of cyclin-D1/CCND1 through mRNA stabilization mechanisms.
Tissue specificity	Ubiquitous.
Posttranslational modification	Citrullinated by PADI4.
Celluar localization	Nucleus;
UniPort	Q9NYF8