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Rabbit Anti-BCL7B Polyclonal Antibody#abs132965

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Description

Catalog-specification	Delivery time	USD price
abs132965-100ug	1-2 Weeks	301.0
abs132965-50ug	1-2 Weeks	201.0

Overview
catalog	abs132965
Description	The development or progression of lung tumors may be influenced by this factor.
Other names	BCL7B, also known as B cell CLL/lymphoma 7B, is a member of the B cell CLL/lymphoma 7 protein family. This protein plays a crucial role in regulating the growth and division of cells in various tissues. BCL7B is involved in the development of lymphocytes and can also act as a tumor suppressor, preventing the uncontrolled growth of cancerous cells. Dysfunction or mutations in BCL7B have been associated with the development of certain cancers, including lymphomas and leukemias. Researchers are currently studying the potential use of BCL7B as a therapeutic target for the treatment of cancer.
Source	Rabbit
Specificity	Total BCL7B levels can be detected by the BCL7B antibody, which specifically targets the endogenous expression of BCL7B.
Species Reactivity	Human;Mouse
Predictive reaction species	Pig;Sheep;Dog;Bovine;
Antigen	BCL7B
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	22 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography, resulting in the production of a highly refined product.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20°C for a year. It is important to avoid any instances of subjecting the product to repeated freeze/thaw cycles. Be mindful of these guidelines to ensure that the product remains in optimal condition.
Storage buffer	（pH 7.4，150mM，0.02%50%）IgG。，。
Target
Background	Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1 (PubMed:25569233). Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation (PubMed:25569233). May play a role in lung tumor development or progression (By similarity).
Tissue specificity	Ubiquitous.
UniPort	Q9BQE9