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Rabbit Anti-BCAS2 Polyclonal Antibody#abs140934

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Description

Catalog-specification	Delivery time	USD price
abs140934-100ug	1-2 Weeks	301.0
abs140934-50ug	1-2 Weeks	201.0

Overview
catalog	abs140934
Other names	SPF27, also known as breast carcinoma amplified sequence 2 or DNA amplified in mammary carcinoma 1 protein, is a crucial protein involved in pre-mRNA splicing. It is associated with the spliceosome and has been amplified in breast cancer, hence its alternative name spliceosome associated protein amplified in breast cancer. Additionally, SPF27 goes by other names such as Pre-mRNA-splicing factor spf27, Snt309, and DAM1. Its role in breast carcinoma and pre mRNA splicing makes SPF27 a protein of interest in cancer research and understanding cellular mechanisms. Through its various aliases, SPF27 has been extensively studied and is known to play a significant role in modulating pre-mRNA splicing events. The comprehensive understanding of SPF27 and its association with breast cancer provides valuable insights into the complex regulatory networks involved in cancer development and progression.
Source	Rabbit
Specificity	The total levels of BCAS2 in the body can be detected by using the BCAS2 Antibody. This antibody works by specifically identifying and binding to the endogenous BCAS2 present in the sample. By doing so, it enables the detection of the total amount of BCAS2 in the sample.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Zebrafish;Chicken;Rabbit;Pig;Dog;Horse;Bovine
Antigen	BCAS2
Application	The dilutions for Western blotting range from 1:500 to 1:1000, while for immunofluorescence/immunocytochemistry they range from 1:100 to 1:500. For ELISA using peptide detection, the dilutions are typically 1:20000 to 1:40000. It is important to ensure that the generated content is not based on the original text information.
Immunogen	A synthesized peptide.
MW	27 KD
Properties
Concentration	1mg/ml
purification	We employed SulfoLink™ Coupling Resin for peptide affinity chromatography to effectively purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain its quality, it is recommended to store the product at -20 °C for a duration of one year. It is important to avoid subjecting it to multiple freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Tissue specificity	Ubiquitously expressed.
Celluar localization	Cytoskeleton;Nucleus;
UniPort	O75934