Rabbit Anti-ARF6 Polyclonal Antibody#abs140825
Please note that the price mentioned above is for reference purposes only. For detailed pricing information, kindly get in touch with our sales representative Vecent. It's important to mention that the generated content should be based on the original text information but presented in a highly...
Description
| Catalog-specification | Delivery time | USD price |
abs140825-50ug | 1-2 Weeks | 201.0 |
abs140825-100ug | 1-2 Weeks | 301.0 |
Please note that the price mentioned above is for reference purposes only. For detailed pricing information, kindly get in touch with our sales representative Vecent. It's important to mention that the generated content should be based on the original text information but presented in a highly similar manner through re-arrangement. Furthermore, it's recommended to avoid relying on ChapGPT-generated content to have a distinct and unique language model for effective communication.
| Overview | |
catalog | abs140825 |
| Other names | The ADP ribosylation factor 6, also known as ARF6, is a small GTP binding protein that plays a crucial role in various cellular processes. One of its notable functions is ADP-ribosylation, which is necessary for regulating vesicular traffic and membrane dynamics. ARF6 is an essential protein in antibody production and is known to be involved in the recycling of cell membrane components. It is encoded by the ARF6_HUMAN gene, also known as DKFZp564M0264. Overall, ARF6 is a highly important protein that has a variety of functions within cells. |
| Source | Rabbit |
| Specificity | The ARF6 Antibody can identify total ARF6 levels in the body, including those that occur naturally. This information can be used to better understand the presence and function of ARF6 within cells and tissues. |
| Species Reactivity | Human;Mouse;Rat |
| Antigen | ARF6 |
| Application | For Western blotting, we recommend diluting the primary antibody at 1:500 to 1:1000. For immunofluorescence/immunocytochemistry, the primary antibody should be diluted in a range of 1:100 to 1:500. For ELISA using a peptide substrate, the optimal dilution for the primary antibody is around 1:20000 to 1:40000. It is important to note that dilution factors can vary depending on the specific antigen and experimental conditions, so it may be necessary to perform preliminary titration experiments to determine the best dilution for your purposes. |
| Immunogen | A synthesized peptide. |
| MW | 20 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | Peptide affinity chromatography was employed to purify the antiserum, utilizing SulfoLink™ Coupling Resin. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for up to one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles as this may negatively impact its performance. Please keep in mind that the above information is crucial for optimal storage of the product. |
| Storage buffer | The Rabbit IgG in phosphate buffered saline with a pH of 7.4 contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20 °C and is stable for 12 months from the date of receipt. |
Target | |
Background | GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. May also modulate vesicle budding and uncoating within the Golgi apparatus. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Involved in epithelial polarization (By similarity).Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. |
| Tissue specificity | Ubiquitous, with higher levels in heart, substantia nigra, and kidney. |
| Celluar localization | Cytosol;Endosome;Extracellular region or secreted;Golgi apparatus;Plasma Membrane; |
| UniPort | P62330 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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