PRAME Polyclonal Antibody #abs117181
Please note that the mentioned price is for your reference only. For detailed pricing information, kindly get in touch with our seller Vecent. It is important to reiterate that the information provided is solely for guidance purposes, and you will need to speak directly with Vecent for accurate...
Description
Catalog-specification | Delivery time | USD price |
abs117181-50ul | In Stock | 228 |
Please note that the mentioned price is for your reference only. For detailed pricing information, kindly get in touch with our seller Vecent. It is important to reiterate that the information provided is solely for guidance purposes, and you will need to speak directly with Vecent for accurate pricing.
Overview | |
Other names | CT130;MAPE;OIP-4;OIP4 |
Source | Rabbit |
Species Reactivity | Human |
Application | WB 1:500 - 1:2000 |
Immunogen | A highly similar content can be generated as follows: A fusion protein composed of a sequence that corresponds to the first 300 amino acids of human PRAME (NP_996839.1) has been recombinantly produced. |
Properties | |
Purification | Affinity purification |
Clonality | Polyclonal Antibody |
Isotype | IgG |
Stability & Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | Store at -20℃. Avoid freeze / thaw cycles. |
Target | |
Background | Melanomas in human beings display a distinctive antigen that is specifically expressed and acknowledged by cytolytic T lymphocytes. Interestingly, this antigen is absent in normal body tissues, except for the testis. The gene responsible for encoding this antigen also acts as a repressor of retinoic acid receptor. By performing this repressive function, the encoded protein provides a growth advantage to cancer cells. It is worth noting that alternative splicing of this gene leads to the production of multiple transcript variants, further adding to its heterogeneity. |
Celluar localization | Cell membrane,Nucleus |
UniPort | P78395 |
Data Examples
The PRAME antibody was utilized for immunofluorescence analysis of U2OS cells. A nuclear staining using DAPI dye was performed, resulting in a blue fluorescence. In order to generate highly similar content, the rearranged version will be as follows: "The U2OS cell line was subjected to immunofluorescence analysis using the PRAME antibody. Nuclear staining was conducted using DAPI dye, resulting in a blue fluorescence signal."
This item is intended solely for use in research and is not approved for diagnostic procedures or for human use. Kindly produce an extensively similar content by rephrasing the above text, while ensuring that the newly generated content remains true to the original context, without adopting the approach of generating content using ChapGPT language models.
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