GLI2 Polyclonal Antibody #abs117211

abs117211-50ul

In Stock

228

Other names

CJS;HPE9;PHS2;THP1;THP2

Source

Rabbit

Species Reactivity

Mouse;Rat

Application

WB 1:500 - 1:2000

Immunogen

Recombinant protein of mouse GLI2

Properties

The mouse lung, brain, heart, ovary, pancreas, and rat brain are all important organs in the body of these small rodents. Each of these organs play a critical role in the overall health and function of the mouse or rat. The lung is responsible for oxygen exchange, the brain for cognition and sensory input, the heart for pumping blood, the ovary for reproductive functions, the pancreas for creating important hormones and enzymes, and the brain for complex neurological processes. Although these organs may seem small and insignificant to us humans, they are vital components of the intricate and delicate ecosystem that is the mouse or rat body.

Properties

Purification

Affinity purification

Clonality

Polyclonal Antibody

Isotype

IgG

Stability & Storage

Store at -20℃. Avoid freeze / thaw cycles.

Storage buffer

Store at -20℃. Avoid freeze / thaw cycles.
A buffer solution of PBS with a pH of 7.3 is made with 0.02% sodium azide and 50% glycerol. This solution is commonly used in laboratory settings and is highly effective in maintaining stable conditions for experiments. The presence of sodium azide prevents bacterial growth, while the glycerol helps to maintain the stability of the solution. The resulting mixture is a viscous liquid that is easy to handle and can be stored for long periods without losing its effectiveness. Overall, this buffer solution is a highly useful tool for researchers looking to maintain consistent and stable conditions in their experiments.

Target

Background

This specific gene encodes a protein belonging to the Gli family's C2H2-type zinc finger protein subclass. Zinc finger motifs in this subclass allow for these transcription factors to bind to DNA through conserved H-C links. Gli family zinc finger proteins function as Sonic hedgehog (Shh) signaling mediators and may play an oncogenic role in embryonal carcinoma cells. The encoded protein localizes to the cytoplasm and boosts patched Drosophila homolog (PTCH) gene expression. Additionally, it may have a critical role during embryogenesis. The protein associated with this gene has been linked to several phenotypes, such as Pallister-Hall syndrome, Greig cephalopolysyndactyly syndrome, postaxial and preaxial polydactyly types A1 and B.

Celluar localization

Cytoplasm,Nucleus

UniPort