ITGBL1 Antibody (Center) #abs111747

abs111747-50ul

In Stock

228

Description

A Polyclonal Antibody (Pab) derived from peptide affinity purification was obtained from rabbits. Reiterating the information in a different manner, but retaining the original context.

Other names

Integrin beta-like protein 1, also known as Osteoblast-specific cysteine-rich protein (OSCP) and Ten integrin EGF-like repeat domain-containing protein (TIED), is a crucial protein that plays a significant role in various cellular functions. ITGBL1 binds with integrins, which are a family of cell surface proteins that mediate cell-to-cell and cell-to-extracellular matrix interactions.
OSCP is specifically expressed in osteoblasts, which are bone-forming cells in the body. It is known to regulate bone formation and mineralization by activating specific signaling pathways. Additionally, TIED contains ten EGF-like repeat domains and is involved in cell adhesion and migration.
Overall, ITGBL1, OSCP, and TIED are highly crucial proteins that are involved in several cellular processes and aid in maintaining the overall health and function of the body.

Source

Rabbit

Specificity

ITGBL1 Antibody is produced by immunizing rabbits with a synthetic peptide derived from the Central region of human ITGBL1. The peptide is conjugated with KLH to enhance immunogenicity. The specific amino acids used in the peptide sequence are between 334 and 360. Our aim is to generate an antibody that recognizes and binds to ITGBL1, enabling its detection and analysis in various research applications.

Species Reactivity

Human

Application

WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50

Properties

Clonality

Polyclonal Antibody

Isotype

Rabbit Ig

Stability & Storage

To ensure optimal conditions, refrigerate the product at 2-8°C for a maximum duration of two weeks. For extended storage, it is recommended to store it at -20°C in small aliquots to prevent any potential damage caused by repeated freeze-thaw cycles.

Storage buffer

The supplied purified polyclonal antibody comes in PBS with a sodium azide concentration of 0.09% (W/V). To obtain this antibody, it undergoes purification using a protein A column, followed by peptide affinity purification.

Research area

Signal Transduction

Target

Celluar localization

Secreted.

UniPort

O95965

References

References

Berg R.W., et.al., Genomics 56:169-178(1999).