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STAT1 Polyclonal Antibody #abs115001

Description

Catalog-specification	Delivery time	USD price
abs115001-50ul	In Stock	228

Please note that the price provided is for reference only. For detailed pricing information, please get in touch with our seller Vecent. It is important to emphasize that the above price is not final and may differ depending on various factors. Therefore, our team at Vecent is always ready to assist you with any inquiries you may have regarding our products and services. Contact us today for a quote and let us help you find the best solution that meets your needs.

Overview
Other names	CANDF7;IMD31A;IMD31B;IMD31C;ISGF-3;STAT91
Source	Rabbit
Species Reactivity	Human;Mouse;Rat
Application	WB 1:500 - 1:2000 IHC 1:50 - 1:200
Immunogen	Our product is a recombinant fusion protein that encompasses amino acids 513-712 of the human STAT1 protein (NP_644671.1). This sequence has been carefully selected to ensure a highly specific and effective result.
Properties	PC-3,HeLa,HepG2,A-549,MCF-7,K-562,Mouse spleen
Properties
Purification	Affinity purification
Isotype	IgG
Stability & Storage	Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. PBS with 0.02% sodium azide, 50% glycerol, pH 7.3 is a commonly used buffer solution. It contains sodium azide to inhibit bacterial growth and glycerol to maintain the stability of proteins or other biomolecules. The pH of the buffer is adjusted to 7.3, which is suitable for many biological experiments. This buffer is often used for various applications, including protein assays, immunostaining, and cell culture. It is important to handle and store this buffer properly, following the necessary safety precautions. By combining these components in the specified proportions, a highly effective and reliable buffer solution is obtained.
Target
Background	This specific gene encodes a protein that belongs to the STAT protein family. Upon stimulation by cytokines and growth factors, receptor associated kinases phosphorylate STAT family members, leading to the formation of homo- or heterodimers. These dimers then migrate to the cell nucleus, where they function as transcription activators. Activation of this protein can occur in response to various ligands, such as interferon-alpha, interferon-gamma, EGF, PDGF, and IL6. Through its actions, this protein regulates the expression of multiple genes, which is crucial for cell survival when facing different cellular stimuli and pathogens. Notably, two different versions of this protein, known as isoforms, are produced through alternative splicing of the gene.
Celluar localization	Cytoplasm,Nucleus
UniPort	P42224