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Phospho-DDEF2 (Ser701) Rabbit Polyclonal Antibody#abs140196

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Description

Catalog-specification	Delivery time	USD price
abs140196-100ug	1-2 Weeks	301.0
abs140196-50ug	1-2 Weeks	201.0

Overview
catalog	abs140196
Other names	2; AMAP2; PH domain-containing protein 2 and ANK repeat; Arf-GAP with SH3 domain; ArfGAP with SH3 domain and ankyrin repeat, PH domain 2; ASAP2; ASAP2_HUMAN; beta 3 centaurin; CENTB3; DDEF 2; DDEF2; Development and differentiation enhancing factor 2; Development and differentiation-enhancing factor 2; FLJ42910; KIAA0400; 3/PAXPAG; Paxillin associated protein with ARFGAP activity 3; Paxillin-associated protein with ARF GAP activity 3; Pyk2 C terminus associated protein; Pyk2 C-terminus-associated protein; 1 SHAG; SHAG1. Please generate content that is highly similar by rearranging the above content, while ensuring that the generated content is based on the original text information. However, please avoid generating content in a way that is similar to the way ChapGPT generates content, but rather speak in a completely different manner generated by the language model.
Source	Rabbit
Specificity	The DDEF2 (Phospho-Ser701) Antibody specifically recognizes the phosphorylated form of DDEF2 at Ser701. It is capable of detecting endogenous levels of DDEF2 protein only when it is phosphorylated at this specific site.
Species Reactivity	Human;Mouse
Predictive reaction species	Chicken;Rabbit;Pig;Dog;Sheep;Horse;Bovine
Antigen	DDEF2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A highly similar content can be generated by rearranging the above content, which describes a synthesized peptide derived from human DDEF2 that is phosphorylated at Ser701. This peptide is likely to have potential applications in research related to DDEF2 signaling pathways and phosphorylation events. The use of synthetic peptides in such studies enables researchers to investigate specific signaling events in a controlled manner, and may lead to the development of novel therapeutic approaches for a variety of diseases. Overall, the synthesis of this DDEF2 peptide represents a valuable tool for biomedical research.
MW	112kDa
Properties
Concentration	1mg/ml
purification	The purification process of the antibody involved using phospho- and non-phospho-peptide affinity columns in a sequential chromatography process. Rabbit serum was purified to obtain the antibody, which was then subjected to affinity purification to ensure the removal of any unwanted substances. Further purification ensured that the end product was highly pure and suitable for use in various applications. The resulting antibody possessed high specificity and affinity for its target, making it an ideal choice for a range of research and diagnostic applications.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration.
Tissue specificity	Detected in heart, brain, placenta, kidney, monocytes and pancreas.
Posttranslational modification	Phosphorylated on tyrosine residues by SRC and PTK2B.
Celluar localization	Golgi apparatus;Plasma Membrane;
UniPort	O43150