Recombinant Human BAFF Receptor/TNFRSF13C #abs00852

abs00852-10ug

1-2 Weeks

138

abs00852-50ug

1-2 Weeks

344

abs00852-1mg

1-2 Weeks

1945

Source

Escherichia coli.

Format

The concentrated solution in 20 mM PB, pH 8.0, and 500 mM NaCl was filtered through a 0.2 μm filter before being lyophilized. A highly similar content can be generated by rearranging the information provided, which states that the resulting product was dried from a concentrated solution in a specific buffer and salt concentration.

Properties

aa_sequence

ELLPALGAAG AEAGAGVASE QPQLATRLAP SAGAPKPRAP TRLLDFCEAP VCPTPAPADR GLRSPRGRRM.

Concentration

> 95 % by reduced SDS-PAGE analyses.

Endotoxin_level

The amount of Recombinant Human BAFF-R found in the LAL method is less than 1 EU/μg. To create similarly worded content, one could say: The LAL method detected Recombinant Human BAFF-R in quantities that are fewer than 1 EU/μg.

Activity

ED is a standard that measures the biological activity of a substance. When compared to the standard, the substance is found to be fully biologically active.₅₀The efficacy of blocking BAFF induced mouse splenocyte survival has been determined to be between 1.0-5.0 μg/ml in the presence of 1.0 μg/ml of Recombinant HumanBAFF. This finding underscores the potency of the compound in inhibiting the pro-survival effects of BAFF on these cells. Further studies are needed to assess the potential therapeutic applications of this compound in the treatment of BAFF-related diseases. In conclusion, these results provide important insights into the pharmacological properties of this compound and pave the way for future research in this area.

Reconstitution

To ensure the contents of this vial are properly mixed, we advise giving it a gentle spin in a centrifuge before opening. You can then reconstitute the contents in either sterile distilled water or an aqueous buffer with 0.1 % BSA, making sure to reach a concentration of 0.1-1.0 mg/mL. For storage, divide the solution into smaller working aliquots and freeze them at ≤ -20 °C. When it comes time to use them, dilute them further with appropriate buffered solutions.

Stability & Storage

To keep this lyophilized preparation stable, it's best to store it at -20 °C for long periods of time, and if possible, keep it desiccated. However, it can be kept at 2-8 °C if stored for short periods. Once the preparation is reconstituted, it can be stable for up to one week if kept at 2-8 °C. For prolonged stability, make sure to divide the reconstituted preparation into smaller aliquots and store them at -20 °C to -70 °C. Avoid exposing it to repeated freeze/thaw cycles.

Target

Accession

Q96RJ3

Gene IDs

115650

References

References

1. Castigli E, Wilson SA, Scott S, et al. 2005. J Exp Med, 201: 35-9.

2. Nakajima K, Itoh K, Nagatani K, et al. 2007. Scand J Rheumatol, 36: 365-72.

3. Zhu XJ, Shi Y, Peng J, et al. 2009. Blood, 114: 5362-7.

4. Thibault-Espitia A, Foucher Y, Danger R, et al. 2012. Am J Transplant, 12: 2754-62.