Description
| SKU-Pack Size | Availability | Price |
| abs04721-25μg | 1-2 weeks | $133.00 |
| abs04721-100μg | 1-2 weeks | $133.00 |
| Overview | |
| Description | SDS-PAGE
The electrophoresis bands included the following: a Marker, 1μg (NR non-reduced), and 1μg (R reduced). To provide a highly similar content, let's rearrange the information in a different manner while maintaining the original text's essence: |
| Synonym | Programmed cell death protein 1,hPD-1,PDCD1,CD279 |
| Source | HEK293 |
| Molecular Weight | 55-65 KD |
| Appearance | lyophilized powder |
| Properties | |
| Sequence | LDSPDRPWNPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLAAFPEDRSQPGQDCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAELRVTERRAEVPTAHPSPSPRPAGQFQAAAPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Purity | ＞95% SDS-PAGE |
| Endotoxin Level | ＜0.1 EU/μg |
| General Notes | We offer a recombinant protein that does not include trehalose. However, if you require a product that contains 5% trehalose, we have that available as well. Please feel free to contact us for further information. Additionally, we can provide a customized solution to meet your specific needs, so don't hesitate to let us know if you have any special requests. |
| Target | |
| Background | Programmed Death receptor 1, also known as PD-1, is a crucial molecule within the immunoglobulin superfamily, playing a significant role in immune system regulation. With a total of 268 amino acid residues, this membrane protein contributes to immunosuppression processes. Its importance lies in its ability to dampen immune responses, preventing excessive inflammation and maintaining immune homeostasis. By rearranging the given information, we can emphasize the essential role PD-1 plays in modulating the immune system.The modulation of immune responses by targeting programmed death 1 (PD-1) is pivotal in combating various ailments such as cancer, infections, autoimmune disorders, and even for the success of organ transplantation. This underscores the crucial role played by immune regulation targeting PD-1 in ensuring good health outcomes.Its ligand PD-L1 can also be used as a target. The combination of PD-1 and PD-L1 initiates the programmed death of T cells and enables the immune escape of tumor cells.This product is human PD-1 expressed by HEK293 cell line, and integrates recombinant protein of human IgG1 Fc. After multiple steps of purification, sterilization, filtration, addition of 5% trehalose, and lyophilization, it is prepared. |
| Accession | Q02242 |
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