SCHIP1 Antibody (Center) #abs101664

abs101664-50ul

In Stock

228

Description

One possible variation is:
We have developed a Rabbit Polyclonal Antibody (Pab) that has been purified using peptide affinity binding. This antibody has high specificity and affinity for its target antigen, making it an excellent tool for various research applications. Using this Pab, researchers can perform accurate and reliable detection, quantification, and localization of the target protein in biological samples. Our Pab has been rigorously tested and characterized to ensure its quality and performance. We provide full technical support and validation data to assist our customers in their experiments. Choose our peptide affinity purified Rabbit Polyclonal Antibody for high-quality and reproducible results in your research.

Other names

SCHIP-1, also known as Schwannomin-interacting protein 1 or SCHIP1, is an essential protein that plays a crucial role in various biological processes. This protein is known for its interactions with Schwannomin, another important protein involved in cellular functions.
SCHIP-1, also referred to as SCHIP1 or Schwannomin-interacting protein 1, is a key player in numerous biological activities. Its significant role lies in its ability to interact with Schwannomin, a pivotal protein influencing critical cellular processes.
In the realm of molecular biology, SCHIP-1, SCHIP1, or Schwannomin-interacting protein 1 stands out as an indispensable component. This protein's relevance stems from its engagement with Schwannomin, an influential protein governing various cellular mechanisms.

Source

Rabbit

Specificity

The SCHIP1 antibody being provided here has been produced through immunization of rabbits with a synthetic peptide that is conjugated with KLH. This particular peptide has been derived from the central region of the human SCHIP1, specifically between amino acids 90-118. To ensure a high level of similarity to the original content, this information has been rearranged and presented in a slightly different form.

Species Reactivity

Human

Application

WB~~1:1000
IHC-P~~1:10~50
FC~~1:10~50

Properties

Clonality

Polyclonal Antibody

Isotype

Rabbit Ig

Stability & Storage

It is recommended to keep the refrigerated at 2-8°C for a duration of 2 weeks. If you need to store it for a longer period, you should store it at -20°C in small aliquots to avoid freeze-thaw cycles.

Storage buffer

This antibody is obtained by purifying a polyclonal antibody using a combination of protein A column and peptide affinity purification methods. It is supplied in PBS with a concentration of 0.09% (W/V) sodium azide as a preservative.

Research area

Cancer;Neuroscience

Target

Background

SCHIP1 is an intriguing protein that forms a specific association with schwannomin, both in laboratory experiments and within living organisms. Its coiled-coil region displays similarities to the coiled-coil regions found in human FEZ proteins and the Caenorhabditis elegans gene product UNC-76. This remarkable discovery opens up new avenues for understanding the functional role of SCHIP1 and its potential involvement in various cellular processes and pathways. By investigating the molecular interactions and mechanisms underlying SCHIP1's association with schwannomin, we can gain insights into the intricate workings of these proteins and their importance in cellular physiology. Excitingly, the identification of SCHIP1 as a coiled-coil protein further underscores the significance of these structural motifs in mediating protein-protein interactions and suggests a potential role for SCHIP1 in regulating critical biological processes. Future studies will undoubtedly delve deeper into the functional significance of SCHIP1 and shed light on its potential implications in human health and disease.

Celluar localization

The location of cytoplasm is where NF2 can also be found, just beneath the cytoplasmic membrane. This indicates that there may be some connection or interaction between the two within this part of the cell. It is important to note this colocalization as it could potentially provide insights into the functions and dynamics of these cellular components.

UniPort

Q9P0W5

References

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
De Jager, P.L., et al. Nat. Genet. 41(7):776-782(2009)