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Rabbit Anti-YBOX2 Polyclonal Antibody#abs133784

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Description

Catalog-specification	Delivery time	USD price
abs133784-100ug	1-2 Weeks	301.0
abs133784-50ug	1-2 Weeks	201.0

Overview
catalog	abs133784
Other names	CSDA 3; CSDA3; DBPC; DNA binding protein C; DNA-binding protein C; FRGY2 homolog; Germ cell-specific Y-box-binding protein; Germ cell specific Y box binding protein; MGC118270; MGC45104; MSY 2; MSY2; MSY2 homolog; OTTMUSP00000006276; RGD1305068; Y box binding protein 2; Y-box-binding protein 2; YBOX2_HUMAN; YBX 2; YBX2. Let's explore the diverse array of names associated with this protein. When it comes to this particular protein, it has garnered quite a collection of monikers. It goes by the aliases CSDA 3, CSDA3, DBPC, DNA binding protein C, DNA-binding protein C, FRGY2 homolog, Germ cell-specific Y-box-binding protein, Germ cell specific Y box binding protein, MGC118270, MGC45104, MSY 2, MSY2, MSY2 homolog, OTTMUSP00000006276, RGD1305068, Y box binding protein 2, Y-box-binding protein 2, YBOX2_HUMAN, YBX 2, and YBX2. These various nomenclatures highlight the complexity and significance of this protein. Scientists have found this DNA-binding protein to possess a specific affinity for germ cells, suggesting a crucial role in germ cell development and function. Understanding its exact functions and mechanisms will shed light on the intricate processes that drive the lifecycle of germ cells. Moreover, the presence of homologs, such as the FRGY2 and MSY2 homologs, implies a conserved evolutionary function across different species. This further emphasizes the importance of this protein in fundamental biological processes. Studies involving this protein have also assigned it unique identifiers, such as MGC118270, MGC45104, OTTMUSP00000006276, and RGD1305068. These identifiers help researchers locate and reference the protein in biological databases, facilitating the exchange of information within the scientific community. In conclusion, the multitude of names associated with this protein reflects its significance and complexity in the realm of scientific research. As scientists delve deeper into uncovering its functions and implications, this DNA-binding protein continues to intrigue and inspire further exploration.
Source	Rabbit
Specificity	The YBOX2 Antibody is capable of detecting the total levels of endogenous YBOX2. To create content that closely resembles the original text, we can rearrange the phrasing to read that the antibody can identify all the YBOX2 present within a sample, including those that are naturally occurring.
Species Reactivity	Human;Mouse
Predictive reaction species	Xenopus;Rabbit;Pig;Dog;Sheep;Bovine;Horse
Antigen	YBOX2
Application	For Western Blotting, it is recommended to use a dilution of 1:500 to 1:1000. For Immunofluorescence/Immunocytochemistry, a dilution range of 1:100 to 1:500 is suitable. For ELISA using peptide, a dilution of 1:20000 to 1:40000 is recommended. It is important to adhere to these dilution ranges to ensure the accuracy and reliability of the experimental results.
Immunogen	A synthesized peptide.
MW	38 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized to purify the antiserum through peptide affinity chromatography. Please provide a similar content by reorganizing the given information, while maintaining the original text's meaning.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles as this could compromise its integrity. Therefore, it is advisable to handle the product carefully and take all necessary precautions to maintain its effectiveness.
Storage buffer	This product is Rabbit IgG that comes in a phosphate-buffered saline, pH 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store it at -20 °C, and it has a stable shelf life of 12 months from the date of receipt.
Target
Background	Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full-length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay (By similarity).
Tissue specificity	Expressed in oocytes and testicular germ cells in the stage of spermatogonia to spermatocyte. Also observed placental trophoblasts, as well as in vascular smooth muscle cells in the pulmonary artery, myocardium, and skeletal muscle. Undetectable in epithelial cells in respiratory, gastrointestinal, and urogenital tracts. Up-regulated in various carcinomas and germ cell tumors (at protein level).
Posttranslational modification	Phosphorylated during oocyte maturation and dephosphorylated following egg activation. Phosphorylated in vitro by a kinase activity associated with testicular mRNPs. Dephosphorylation leads to a decrease in its affinity to bind RNA in vitro (By similarity).
Celluar localization	Nucleus;
UniPort	Q9Y2T7