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Rabbit Anti-VASH1 Polyclonal Antibody#abs135124

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Description

Catalog-specification	Delivery time	USD price
abs135124-100ug	1-2 Weeks	301.0
abs135124-50ug	1-2 Weeks	201.0

Overview
catalog	abs135124
Other names	One possible rearrangement could be: Vasohibin 1 is also known as KIAA1036, VASH, or VASH1. It is a protein encoded by the VASH1 gene in humans. Vasohibin-1 is a regulator of angiogenesis (the formation of new blood vessels) and may also play a role in tumor growth. Despite its name, VASH1 is not the only member of the Vasohibin family, as there is also a VASH2 protein. However, VASH1 is the most studied and well-known member of the family.
Source	Rabbit
Specificity	The total levels of endogenous VASH1 can be accurately detected using the VASH1 Antibody. To provide similar content, the following information is rearranged based on the original text: The VASH1 Antibody is capable of precisely identifying the overall levels of VASH1 naturally present in an organism.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Rabbit;Sheep;Dog;Horse;Bovine
Antigen	VASH1
Application	。，Western Blot，1:500~1:1000。/，1:100-1:500。(ELISA)1:20000-1:40000。，，ChapGPT，。
Immunogen	A synthesized peptide.
MW	40 KD
Properties
Concentration	1mg/ml
purification	A purification process called peptide affinity chromatography was employed using the SulfoLink™ Coupling Resin to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality, keep the store at -20 °C for one year without subjecting it to freeze/thaw cycles repeatedly. Let's generate a significantly different version of the original text using a language model approach, rather than following ChapGPT's content generation method. "Maintain the storage temperature at -20 °C consistently over a period of one year to ensure optimum preservation. It is crucial to avoid subjecting the stored items to repeated freezing and thawing cycles."
Storage buffer	This Rabbit IgG comes in a solution of phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended that the solution be stored at a temperature of -20 °C to maintain stability for up to 12 months from the date of receipt.
Target
Background	Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity.
Tissue specificity	Preferentially expressed in endothelial cells. Highly expressed in fetal organs. Expressed in brain and placenta, and at lower level in heart and kidney. Highly detected in microvessels endothelial cells of atherosclerotic lesions.
Posttranslational modification	2 major forms (42 and 36 kDa) and 2 minors (32 and 27 kDa) may be processed by proteolytic cleavage. The largest form (42 kDa) seems to be secreted and the other major form (63 kDa) seems to accumulate within the cells or pericellular milieu. Polypeptide consisting of Met-77 to Arg-318 may correspond to the 27 kDa form and that consisting of Met-77 to Val-365 may correspond to the 36 kDa form.Ubiquitinated in vitro.
Celluar localization	Endoplasmic reticulum;Extracellular region or secreted;
UniPort	Q7L8A9