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Rabbit Anti-TUSC5 Polyclonal Antibody#abs133647

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Description

Catalog-specification	Delivery time	USD price
abs133647-100ug	1-2 Weeks	301.0
abs133647-50ug	1-2 Weeks	201.0

Overview
catalog	abs133647
Other names	Lost at seventeen The tumor suppressor candidate known as Tusc5, also referred to as Dispanin subfamily B member 1 or DSPB1, plays a crucial role in inhibiting tumor growth. Located at the chromosomal region 17p13.3, Tusc5 is an interferon-induced transmembrane domain-containing protein D3. Its function is vital for maintaining cellular homeostasis and preventing the development of cancer. With its unique properties and potential therapeutic applications, Tusc5 continues to intrigue researchers in the field.
Source	Rabbit
Specificity	The TUSC5 Antibody is capable of identifying total TUSC5 levels that are already present in the body. With this, it enables scientists and researchers to have a clearer understanding of the endogenous levels of TUSC5.
Species Reactivity	Human
Antigen	TUSC5
Application	The recommended dilution range for Western Blot is between 1:500 to 1:1000, while for Immunofluorescence/Immunocytochemistry, it is between 1:100 to 1:500. For ELISA (peptide), the suggested dilution range is between 1:20000 to 1:40000. It is important to follow these recommendations to obtain accurate and reliable results in your experiments.
Immunogen	A synthesized peptide.
MW	22 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. The resulting product was highly refined and ready for use in further experiments.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is recommended to keep the product at a temperature of -20 °C for one year. It is important to avoid subjecting the product to repeated cycles of freezing and thawing as this can have an adverse effect on its stability and potency. By following these guidelines, you can help to maintain the integrity of the product and ensure that it remains effective for its intended use.
Storage buffer	The provided information states that the Rabbit IgG is preserved in phosphate buffered saline with a pH of 7.4. It contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. To maintain its properties, it should be stored at a temperature of -20 °C. Its stability is guaranteed for a period of 12 months starting from the date of receipt.
Target
Background	May be involved in fat metabolism.
Tissue specificity	Expressed at high levels in heart, mammary gland, adrenal gland, stomach, smooth muscle and skeletal muscle, and at lower levels in brain and lung. Strongly down-regulated in lung cancer tissues, due to hypermethylation of the corresponding locus.
Celluar localization	Plasma Membrane;
UniPort	Q8IXB3