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Rabbit Anti-TSLP Polyclonal Antibody#abs137554

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Description

Catalog-specification	Delivery time	USD price
abs137554-100ug	1-2 Weeks	301.0
abs137554-50ug	1-2 Weeks	201.0

Overview
catalog	abs137554
Other names	The Thymic stromal lymphopoietin (TSLP) is a protein that plays a significant role in immune responses. TSLP is produced by different tissues throughout the body, including the thymus, skin, lungs, and gut. This protein acts as a cytokine, which means it can trigger a chain reaction that leads to inflammation and immune response. It can also activate dendritic cells, which are essential cells in the immune system, to promote the differentiation of T cells, B cells, and natural killer cells. TSLP is an important mediator in allergic reactions, asthma, and different types of cancers. Understanding its biological functions can help in the development of novel therapies for these diseases.
Source	Rabbit
Specificity	The TSLP Antibody is capable of identifying the complete amount of naturally occurring TSLP in a particular sample. This means the antibody is designed to target and detect the total levels of TSLP present in a given system or organism.
Species Reactivity	Human;Mouse;Rat
Antigen	TSLP
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human TSLP.
MW	18 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum went through purification via peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	One year of storage is recommended at -20 °C. It is important to avoid subjecting the stored material to multiple freeze and thaw cycles.
Storage buffer	The rabbit IgG is formulated in a solution of phosphate buffered saline, pH 7.4, and contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. To ensure its stability, store the product at -20 °C, and it will remain stable for up to 12 months from the date of receipt.
Target
Background	Isoform 1 is a cytokine that has the ability to stimulate monocytes and induce the release of chemokines that attract T-cells. Additionally, it plays a crucial role in enhancing the maturation of dendritic cells marked by CD11c expression. On another note, this cytokine has the potential to trigger mast cells and initiate allergic inflammation.
Tissue specificity	Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva.
Celluar localization	Extracellular region or secreted;
UniPort	Q969D9