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Rabbit Anti-TRAM2 Polyclonal Antibody#abs137718

Rabbit Anti-TRAM2 Polyclonal Antibody#abs137718 Please note that the price mentioned above is simply for your reference, for more detailed pricing information, we suggest you connect with our sales representative Vecent. It is crucial to note that any pricing information provided here is subject...

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Description

Catalog-specification	Delivery time	USD price
abs137718-100ug	1-2 Weeks	301.0
abs137718-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is simply for your reference, for more detailed pricing information, we suggest you connect with our sales representative Vecent. It is crucial to note that any pricing information provided here is subject to change. Therefore, we advise you to get in touch with Vecent for the latest quote.

Overview
catalog	abs137718
Other names	KIAA0057, also known as C330003D03Rik, MGC25725, or OTTHUMP00000016607, is a Translocating chain-associated membrane protein 2 (TRAM2). This protein plays a crucial role in translocation processes within the cell membrane. TRAM2_HUMAN is the designated symbol for Translocation associated membrane protein 2. With its unique structure and function, TRAM2 contributes to the intricate cellular mechanisms. It is essential for maintaining proper membrane protein localization and facilitating efficient transfer of key biomolecules. The significance of TRAM2 underscores the importance of understanding its role and exploring its potential implications in various biological processes.
Source	Rabbit
Specificity	The endogenous levels of total TRAM2 can be accurately detected by the TRAM2 Antibody. By rearranging the existing content, a highly similar version can be generated.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Chicken;Rabbit;Pig;Dog;Horse
Antigen	TRAM2
Application	The recommended dilutions for WB are 1:1000-3000, for IHC are 1:200, and for ELISA using peptide are 1:20000-1:40000. It is important to adhere to these dilutions to ensure accurate and reliable results.
Immunogen	A synthesized peptide derived from human TRAM2.
MW	43 kDa
Properties
Concentration	1mg/ml
purification	The purification process of the antiserum involved the use of SulfoLink™ Coupling Resin in peptide affinity chromatography. This enabled the separation of the desired molecules from other unwanted ones. The procedure ensured that a highly purified formulation of the antiserum was obtained, which met the required standards for quality and efficacy.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated cycles of freezing and thawing. Ensuring adherence to these storage guidelines will help preserve the integrity and effectiveness of the product.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Necessary for collagen type I synthesis. May couple the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+ concentration at the site of collagen synthesis, and a high Ca2+ concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT) (PubMed:27499293).
UniPort	Q15035