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Rabbit Anti-SDCG1 Polyclonal Antibody#abs133334

Please note that the price mentioned above is for your reference only. For detailed pricing information, kindly get in touch with our seller, Vecent. We recommend reaching out to Vecent for specific pricing details. Western blot analysis of extracts from HUVEC cells, using SDCG1 antibody. This...

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Description

Catalog-specification	Delivery time	USD price
abs133334-100ug	1-2 Weeks	301.0
abs133334-50ug	1-2 Weeks	201.0

Overview
catalog	abs133334
Other names	1. FLJ10051, also known as SDCCAG1, is a protein that plays a role in nuclear export mediation and is commonly referred to as Nemf (Nuclear export mediator factor Nemf). 2. The gene 1500011I12Rik, along with the gene 4933405E14Rik, is associated with Antigen NY-CO-1, a serologically defined colon cancer antigen. 3. It is worth noting that NY-CO-1 has been identified as a potential biomarker for colon cancer. 4. The protein NEMF is encoded by the NEMF_HUMAN gene and has been studied for its implications in various cellular processes. 5. The discovery of NY-CO-1 and its association with colon cancer has brought a new perspective to the field of cancer research. 6. FLJ10051, also known as SDCCAG1, has been found to interact with other proteins involved in cellular pathways, further highlighting its significance. 7. The identification of Nemf as a nuclear export mediator factor has shed light on the mechanisms of protein trafficking within cells. 8. The role of Nemf in the context of cancer progression and its potential as a therapeutic target are areas of active investigation. 9. The serological detection of NY-CO-1 in colon cancer patients holds promise for improved diagnosis and monitoring of the disease. 10. The study of NY-CO-1 and its related genes, such as 1500011I12Rik and 4933405E14Rik, provides valuable insights into the molecular mechanisms underlying colon cancer.
Source	Rabbit
Specificity	The endogenous levels of total SDCG1 can be detected by the SDCG1 Antibody. A content that is highly similar can be generated by rearranging the original text information.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Rabbit;Pig;Dog;Sheep;Bovine;Horse
Antigen	SDCG1
Application	To use western blotting, dilution ratios of 1:500 to 1:1000 are recommended. For IF/ICC, dilution ratios of 1:100 to 1:500 are suggested. When using ELISA with a peptide, dilution ratios of 1:20000 to 1:40000 are appropriate. It is important to carefully consider the appropriate dilution ratios for each individual experiment to obtain accurate and reliable results.
Immunogen	A synthesized peptide.
MW	123 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was refined through peptide affinity chromatography. A highly comparable statement can be formed by rearranging the original content while maintaining the same information.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the product's quality, it is recommended to store it at a temperature of -20 °C for a duration of one year. Avoid exposing the product to multiple freeze/thaw cycles as this may affect its efficacy.
Storage buffer	This is a description of Rabbit IgG in a solution containing phosphate buffered saline with a pH of 7.4. The solution also contains 150mM NaCl, as well as 0.02% sodium azide and 50% glycerol. The storage temperature for this solution is -20 °C, with the solution being stable for up to 12 months from the date of receipt.
Target
Background	Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex (PubMed:25578875). May indirectly play a role in nuclear export (PubMed:16103875).
Tissue specificity	Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis.
Celluar localization	Nucleus;
UniPort	O60524