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Rabbit Anti-TPO Polyclonal Antibody#abs137756

Please note that the price mentioned here is only for your reference. For detailed information on prices, kindly get in touch with our representative, Vecent. Thank you. Western blot analysis TPO using HuvEc whole cell lysates This product is for research use only, not for use in diagnostic...

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Description

Catalog-specification	Delivery time	USD price
abs137756-100ug	1-2 Weeks	301.0
abs137756-50ug	1-2 Weeks	201.0

Please note that the price mentioned here is only for your reference. For detailed information on prices, kindly get in touch with our representative, Vecent. Thank you.

Overview
catalog	abs137756
Other names	Thyroid peroxidase, also known as TPO or TPX, is a thyroid microsomal antigen that plays an important role in thyroid hormone synthesis. Its gene, TDH2A, is expressed in the thyroid gland and codes for the production of TPO. Any autoantibodies formed against TPO are known as thyroid microsomal antibodies (MSA). These MSA can be used as a diagnostic tool for autoimmune thyroiditis and thyroid dysfunction.
Source	Rabbit
Specificity	The TPO Antibody is capable of detecting total TPO at endogenous levels. This means that the antibody is able to identify the full range of TPO present in a sample, without the need for additional amplification or manipulation. The detection of total TPO using this antibody provides a reliable and accurate measure of TPO levels, which can be used for research, diagnosis, and treatment of various diseases and conditions. With its high sensitivity and specificity, the TPO Antibody is an essential tool for scientists and healthcare professionals working in the field of thyroid function and related disorders.
Species Reactivity	Human
Predictive reaction species	Pig;Dog;Horse
Antigen	TPO
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human TPO.
MW	102 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography to purify the antiserum. Let me provide you with another version of the text that maintains the essence of the original information while being distinct in its presentation: By employing SulfoLink™ Coupling Resin, an effective purification technique involved peptide affinity chromatography to isolate the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain its quality, store it at -20 °C for a year. Make sure to avoid subjecting it to multiple freeze/thaw cycles.
Storage buffer	This rabbit IgG is stored in a solution of phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended that it be kept at a temperature of -20 °C to maintain its stability, which is guaranteed for 12 months after receipt.
Target
Background	Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T3 and T4.
Posttranslational modification	Glycosylated.Heme is covalently bound through a H2O2-dependent autocatalytic process. Heme insertion is important for the delivery of protein at the cell surface.Cleaved in its N-terminal part.
Celluar localization	Extracellular region or secreted;Mitochondrion;Plasma Membrane;
UniPort	P07202