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Rabbit Anti-TNP2 Polyclonal Antibody#abs139233

Please note that the price provided is only for your reference and for more detailed pricing information, we kindly ask you to contact our seller Vecent. Western blot analysis TNP2 using A549 whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in...

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Description

Catalog-specification	Delivery time	USD price
abs139233-100ug	1-2 Weeks	301.0
abs139233-50ug	1-2 Weeks	201.0

Please note that the price provided is only for your reference and for more detailed pricing information, we kindly ask you to contact our seller Vecent.

Overview
catalog	abs139233
Other names	The protein known as Nuclear Transition Protein 2, or TNP2, is an important player in the process of histone to protamine replacement. It is also sometimes referred to as TP 2 or TP2. During this replacement, TNP2 acts as a transition protein that helps to facilitate the exchange of histones for protamines. Understanding the function of TNP2 is important for understanding the complex processes involved in chromatin remodeling. By rearranging the original text, we can see that TNP2 is a critical player in the conversion of histones to protamines, and is often referred to by several different names, including TP 2 and TP2. Its role in facilitating chromatin remodeling is key to understanding the complex processes of gene expression and regulation.
Source	Rabbit
Specificity	The TNP2 Antibody is designed to identify total TNP2 levels that occur naturally in the body. It is a reliable tool for detecting the endogenous presence of TNP2. By utilizing this antibody, researchers can accurately study and analyze the total amount of TNP2 present in biological samples. This facilitates a better understanding of the functions and roles played by TNP2 in various biological processes.
Species Reactivity	Human
Antigen	TNP2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human TNP2.
MW	16 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain quality, the product should be stored at -20 °C for one year, while ensuring there are no repeated freeze/thaw cycles.
Storage buffer	The provided content cannot be rearranged to generate a highly similar content as it is already concise and covers all the necessary information. However, I can provide alternative phrasing: Rabbit IgG is suspended in phosphate buffered saline (PBS) with a pH of 7.4. The solution contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20 °C for optimum stability. The product remains stable for 12 months starting from the date of receipt.
Target
Background	In the process of spermatid development in mammals, an essential role is played by the replacement of histones with protamine. This crucial process involves the involvement of specific factors, among which a key player is a protein responsible for facilitating the transition. This protein actively participates in the relocation of histones and initiation of protamine assembly in elongating spermatids. Additionally, it binds to nucleosomes in condensing spermatids, aiding in the recruitment and processing of protamines. These protamines are pivotal for evicting histones and delivering a compacted DNA structure, enabling the formation of fully functional sperm cells. The participation of this protein in the intricate process of histone-to-protamine replacement demonstrates its significance in the successful development of mature spermatozoa.
Tissue specificity	Expressed by spermatids (at protein level).
Celluar localization	Nucleus;
UniPort	Q05952