Rabbit Anti-TM16G Polyclonal Antibody #abs130486

abs130486-50ug

1-2 Weeks

201

abs130486-100ug

1-2 Weeks

301

Description

It is possible that this protein serves as a chloride channel that is activated by calcium. Additionally, it may also be involved in facilitating interactions between cells.

Other names

Anoctamin 7, also known as ANO7_HUMAN, is a protein that belongs to the transmembrane protein 16G family. It is encoded by the DTMPP gene, which is also known as Dresden transmembrane protein of the prostate. ANO7 is expressed in the prostate gland and has been identified as a new gene expressed in prostate (NGEP). The protein is also known as IPCA-5 or PCANAP5 and is associated with prostate cancer. ANO7 plays a role in ion transport across the cell membrane and is believed to be involved in the regulation of a variety of physiological processes. Despite its importance, the exact mechanism of ANO7 action is not well understood and further research is needed to fully understand its function.

Source

Rabbit

Specificity

TM16G Antibody detects endogenous levels of TM16G.

Species Reactivity

Human

Application

The recommended dilutions for IHC are 1:50-1:200, while for IF/ICC they are 1:100-1:500. In the case of ELISA with a peptide, the recommended dilutions range from 1:20000 to 1:40000. It is important to carefully consider these dilution factors to ensure optimal results in your experiments.

Immunogen

A synthesized peptide derived from human TM16G.

Properties

Concentration

1mg/ml

Purification

SulfoLink™ Coupling Resin was utilized in the peptide affinity chromatography process to purify the antiserum.

Clonality

Polyclonal Antibody

Stability & Storage

To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles.

Storage buffer

This product contains Rabbit IgG in a solution of phosphate buffered saline at a pH of 7.4. It also contains 150mM of NaCl, 0.02% sodium azide, and 50% glycerol. For optimal storage, this product should be stored at -20°C, and it has a shelf life of 12 months from the date of purchase. Please note that the information presented here is based on the original text, but has been rearranged in a similar manner to convey the same information.

Target

Background

The protein has the ability to scramble certain phospholipids, including phosphatidylserine, phosphatidylcholine, and galactosylceramide, in a calcium-dependent manner. Despite its name, it does not exhibit any calcium-activated chloride channel activity. Its function may involve participating in cell-cell interactions.

Tissue specificity

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Celluar localization

The plasma membrane surrounds the cell, while the cytosol is the liquid found inside the cell. The endoplasmic reticulum, a network of membranes, is responsible for the transport of proteins and lipids. The nucleus, the cell's control center, contains genetic material and controls all of the cell's activities.

UniPort

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