Rabbit Anti-TEAD1 Polyclonal Antibody#abs133443
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Description
| Catalog-specification | Delivery time | USD price |
abs133443-100ug | 1-2 Weeks | 301.0 |
abs133443-50ug | 1-2 Weeks | 201.0 |
Please note that the price mentioned is only a reference. For detailed pricing information, please get in touch with our sales representative, Vecent. It's important to refrain from using ChapGPT to generate similar content and instead generate text in a completely different manner.
| Overview | |
catalog | abs133443 |
| Other names | 1. Protein GT-IIC, also known as SV40 transcriptional enhancer factor, is a member of the TEA domain family. Other members of this family include TEA domain family members 1, 2, 3, and 4, as well as TEAD 1, TEAD 2, TEAD 3, TEAD 4, TEAD2, TEAD3, TEAD4, and TEAD5. 2. TCF 13, TEF1, TEF4, and TEF5 are also transcription factors that play important roles in gene regulation. 3. Transcription factor 13 and transcription factor 13 like 1 are additional members of this family. 4. Transcription factor RTEF 1, transcriptional enhancer factor TEF 1, TEF 3, TEF 4, and TEF 5 are all involved in the regulation of gene expression. Overall, these proteins and transcription factors belong to the TEA domain family and play important roles in transcriptional regulation. |
| Source | Rabbit |
| Specificity | Total TEAD1 levels can be detected using the TEAD1 antibody, which is capable of recognizing endogenous TEAD1. The antibody enables the reliable measurement of TEAD1 levels present within biological samples. |
| Species Reactivity | Human;Mouse;Rat |
| Predictive reaction species | Xenopus;Rabbit;Sheep;Dog;Horse;Bovine; |
| Antigen | TEAD1 |
| Application | The dilution ranges for WB are from 1:500 to 1:1000, for IHC it is from 1:50 to 1:200, for IF/ICC it is from 1:100 to 1:500, and for ELISA(peptide) it is from 1:20000 to 1:40000. You can adjust the dilution factor according to your experimental needs. |
| Immunogen | A synthesized peptide. |
| MW | 48 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | Purification of the antiserum was carried out using SulfoLink™ Coupling Resin through peptide affinity chromatography. The method resulted in a highly purified antiserum. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles |
| Storage buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl,sodium azide and glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
Target | |
Background | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif. |
| Tissue specificity | Preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart. |
| Celluar localization | Nucleus; |
| UniPort | P28347 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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