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Rabbit Anti-SYTL4 Polyclonal Antibody#abs134857

Please be advised that the given price is only a reference and for further details, kindly get in touch with our seller, Vecent. Feel free to reach out to him for accurate and precise pricing information. Western blot analysis of extracts from 3T3 cells, using SYTL4 antibody. This product is for...

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Description

Catalog-specification	Delivery time	USD price
abs134857-100ug	1-2 Weeks	301.0
abs134857-50ug	1-2 Weeks	201.0

Overview
catalog	abs134857
Other names	Exophilin-2, also known as Granuphilin or FLJ40960, is a protein encoded by the gene DKFZp451P0116 in humans. It belongs to the family of Synaptotagmin-like (Slp) proteins and is denoted by the symbol Sytl4. This protein plays an essential role in the exocytosis of insulin granules in pancreatic Beta cells, and it functions as a calcium sensor. The protein's structure is similar to that of Synaptotagmins, which are involved in regulating neurotransmitter release. Exophilin-2 is primarily found in the secretory vesicles of insulin-secreting cells, indicating its function in the insulin secretion pathway. Therefore, this protein is crucial for the regulation of glucose homeostasis.
Source	Rabbit
Specificity	Endogenous levels of total SYTL4 can be accurately identified using the SYTL4 Antibody.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Rabbit;Pig;Dog;Sheep;Bovine;Horse
Antigen	SYTL4
Application	For Western blotting, we recommend diluting 1:500~1:1000. When performing IF/ICC, a dilution range of 1:100-1:500 is suggested. For ELISA using a peptide, we advise a dilution range of 1:20000-1:40000. It is important to note that these dilution recommendations are based on the original text information and should be followed accordingly.
Immunogen	A synthesized peptide.
MW	76 KD
Properties
Concentration	1mg/ml
purification	We utilized SulfoLink™ Coupling Resin for peptide affinity chromatography to purify the antiserum. Let's generate a completely different content using the language model, rather than following the method used for generating content in ChapGPT conversations.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the integrity of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. Avoid subjecting it to repeated cycles of freezing and thawing, as this may compromise its quality and efficacy. It is crucial to follow these guidelines to ensure optimal performance and durability of the product.
Storage buffer	The storage recommendation for Rabbit IgG is to store it at -20 °C in phosphate buffered saline with pH 7.4. It should be stored in a solution containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. The stability of Rabbit IgG is guaranteed for 12 months from the time of receipt.
Target
Background	Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca2+-independent manner (By similarity).
Celluar localization	Cytoskeleton;Cytosol;Endosome;Nucleus;Plasma Membrane;
UniPort	Q96C24