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Rabbit Anti-SOX12 Polyclonal Antibody#abs138277

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Description

Catalog-specification	Delivery time	USD price
abs138277-100ug	1-2 Weeks	301.0
abs138277-50ug	1-2 Weeks	201.0

Overview
catalog	abs138277
Other names	Protein SOX-22, also known as Homo sapiens SRY (sex determining region Y) box 12 or SOX12 protein, plays a crucial role in genetic regulation. SOX 12 protein, encoded by the SOX12 gene, belongs to the SRY-related HMG box gene family. As a transcription factor, SOX 12 is involved in various biological processes. The SRY (sex determining region Y) box 12, identified as SRY box 22 or SOX22 protein, exhibits functional diversity and versatility. By rearranging the above content, we can explore the unique characteristics of SOX 12 and SOX 22 further. The transcription factor SOX 12, also referred to as Transcription factor Sox-12 or Transcription factor SOX 12, is an essential player in genetic regulation. Its role in gene expression and developmental processes is paramount. With its evolutionarily conserved DNA binding domain, SOX 12 protein demonstrates remarkable flexibility and adaptability. The SRY (sex determining region Y) box 12 and SRY (sex determining region Y) box 22, both encompassing the potent SOX 12 protein, contribute significantly to the intricate networks of genetic control. Understanding the intricate functions of SOX 12 and SOX 22 is crucial for deciphering their impacts on cellular differentiation and tissue development. These transcription factors exhibit distinct expression patterns and target genes, offering a dynamic framework for gene regulation. The SOX12 gene, encoding SOX12 protein, has been implicated in various physiological processes, such as neurogenesis and skeletal development. Similarly, SOX22 protein, arising from the SRY Box 22 gene, influences genetic programs associated with cellular proliferation and differentiation. The multifaceted nature of SOX 12 and SOX 22 proteins underscores their significance in diverse biological contexts. Unraveling their regulatory mechanisms and interactions with other molecules will shed light on their precise roles in development and disease. The research on SOX 12 and SOX 22 opens up exciting avenues for understanding the complexity of gene regulation and paves the way for potential therapeutic interventions targeting these key players.
Source	Rabbit
Specificity	The detection of total SOX12 at endogenous levels is facilitated by the SOX12 Antibody. Can you generate a dialogue using a language model that produces content distinct from the original text?
Species Reactivity	Human;Mouse
Predictive reaction species	Pig;Dog;
Antigen	SOX12
Application	The recommended dilutions for using our antibodies are: 1:1000-3000 for Western Blotting and 1:100-1:500 for IF/ICC. For ELISA with peptide, we suggest a dilution of 1:20000-1:40000. These dilutions have been tested in our lab and have shown reliable and consistent results. We believe that this information will be helpful in optimizing your experiments and achieving high-quality data.
Immunogen	A synthesized peptide derived from human SOX12.
MW	34 kDa
Properties
Concentration	1mg/ml
purification	We employed SulfoLink™ Coupling Resin in the process of peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to keep the product at a temperature of -20 °C for a period of one year. It is important to avoid exposing the product to repeated freeze/thaw cycles. This will help preserve the integrity and quality of the product. It is advisable to follow these guidelines for the safe and effective storage of the product.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Binds to the sequence 5'-AACAAT-3'.
Tissue specificity	Expressed most abundantly in the CNS. Also expressed in fetal brain and kidney and adult heart, pancreas, testis and ovary. Other tissues were only weakly positive.
Celluar localization	Nucleus;
UniPort	O15370