Rabbit Anti-FNTB Polyclonal Antibody#abs134641
Please note that the mentioned price is for your reference only. For detailed pricing information, we advise you to get in touch with our sales representative, Vecent. Do not hesitate to reach out to him for accurate pricing details. This product is for research use only, not for use in...
Description
| Catalog-specification | Delivery time | USD price |
abs134641-100ug | 1-2 Weeks | 301.0 |
abs134641-50ug | 1-2 Weeks | 201.0 |
Please note that the mentioned price is for your reference only. For detailed pricing information, we advise you to get in touch with our sales representative, Vecent. Do not hesitate to reach out to him for accurate pricing details.
| Overview | |
catalog | abs134641 |
| Other names | Farnesyltransferase CAAX subunit beta, also known as CAAX farnesyltransferase subunit beta or FTase beta, is an enzyme that plays a crucial role in protein prenylation. Its enzymatic activity, classified under EC 2.5.1.58, involves the transfer of a farnesyl group to a designated protein substrate. This process is essential for the correct localization and function of various proteins, including Ras proteins. The gene encoding CAAX farnesyltransferase subunit beta in humans is designated FNTB. Other names for this protein include farnesyltransferase CAAX box beta1, farnesyltransferase, CAAX box, beta, FPTB, FTase-beta, and Ras proteins prenyltransferase subunit beta. The protein is also denoted by its respective UniProtKB entry, FNTB_HUMAN, and the gene symbol MGC105303. Understanding the role of CAAX farnesyltransferase subunit beta is important in various biological processes and diseases associated with protein prenylation. Manipulating the activity of this enzyme could provide insights into the development of potential therapeutic strategies targeting Ras proteins and related pathways. |
| Source | Rabbit |
| Specificity | The FNTB Antibody is capable of identifying the complete quantity of endogenous FNTB that is present within a sample. The content generated should be based on this information, but the wording can be rearranged to create a unique output. |
| Species Reactivity | Human;Mouse;Rat |
| Predictive reaction species | Rabbit;Pig;Dog;Bovine; |
| Antigen | FNTB |
| Application | For Western Blot analysis, the recommended dilution range is between 1:500 to 1:1000. For immunofluorescence and immunocytochemistry applications, the diluted concentration range is between 1:100 to 1:500. For peptide-based ELISA assays, the suggested dilution range is between 1:20000 to 1:40000. It is important to note that dilutions may vary depending on the specific experiment and the quality of the primary antibody used. |
| Immunogen | A synthesized peptide. |
| MW | 49 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | Using SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. This process allowed for the removal of impurities, resulting in a highly purified product. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To ensure preservation, it is recommended to store at a temperature of -20 °C for a duration of one year. To prevent damage, it is important to avoid subjecting it to multiple freeze/thaw cycles. |
| Storage buffer | This product consists of rabbit IgG dissolved in a solution containing phosphate buffered saline at a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store the product at a temperature of -20 °C. As long as stored properly, the product will remain stable for up to 12 months from the date of receipt. |
Target | |
Background | Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. |
| Celluar localization | Cytoskeleton;Cytosol; |
| UniPort | P49356 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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