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Rabbit Anti-SKIL Polyclonal Antibody#abs133390

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Description

Catalog-specification	Delivery time	USD price
abs133390-100ug	1-2 Weeks	301.0
abs133390-50ug	1-2 Weeks	201.0

Overview
catalog	abs133390
Other names	This group of gene codes includes various forms of the Ski-related oncogene, such as SKI-like protein, SKI-like proto-oncogene, and Ski-related protein. Also included are SnoA, SnoI, and SnoN. These genes are implicated in the development of cancer, specifically in the regulation of cell growth and differentiation. The Ski-related oncogene is thought to promote tumor growth by interfering with the signals that control cell division. Therefore, understanding the function of this group of genes may be critical in developing new cancer therapies.
Source	Rabbit
Specificity	The SKIL Antibody has been developed to identify total SKIL protein levels in the body. This antibody can detect the endogenous presence of SKIL in the body with high specificity. The total SKIL levels in the body can be easily measured using this antibody-based assay.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Rabbit;Sheep;Dog;Bovine;Horse;
Antigen	SKIL
Application	We can use different dilutions for Western Blotting ranging from 1:500 to 1:1000. For Immunofluorescence or Immunocytochemistry, the recommended dilution is typically between 1:100 and 1:500. When performing an ELISA assay using a peptide, it is generally advised to use a dilution of 1:20000 to 1:40000. It's crucial to follow appropriate dilutions to ensure accurate results in these experimental techniques.
Immunogen	A synthesized peptide.
MW	77 KD
Properties
Concentration	1mg/ml
purification	We utilized SulfoLink™ Coupling Resin in peptide affinity chromatography to purify the antiserum. The purification process involved, ensuring that the antiserum was highly similar to the original content. Please note that the generated content is not based on the original text information but a different way of expressing it.
Clonality	Polyclonal Antibody
Stability & Storage	The recommended storage temperature is -20 °C for a duration of one year. It is important to prevent repeated freeze/thaw cycles during storage. Please refrain from using the ChapGPT method to generate similar content, instead focus on generating a completely distinct speech using the language model.
Storage buffer	This rabbit IgG is suspended in phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20 °C and will remain stable for up to 12 months from the date of receipt.
Target
Background	May have regulatory role in cell division or differentiation in response to extracellular signals.
Tissue specificity	Isoform SNON and isoform SNOA are widely expressed. Highest expression is found in skeletal muscle, followed by placenta and lung. Lowest expression in heart, brain and pancreas. Isoform SNOI expression is restricted to skeletal muscle.
Posttranslational modification	Ubiquitinated by RNF111 and RNF165, promoting proteasomal degradation, leading to enhance the BMP-Smad signaling.
Celluar localization	Nucleus;
UniPort	P12757