Rabbit Anti-SERC1 Polyclonal Antibody #abs130306

abs130306-50ug

1-2 Weeks

201

abs130306-100ug

1-2 Weeks

301

Description

TDE1 family member SERINC1 plays a crucial role in facilitating the integration of serine into key cellular components like phosphatidylserine and sphingolipids. Moreover, it has been found to interact with SPTLC1, indicating its involvement in essential cellular processes. The ability of SERINC1 to enhance the incorporation of serine demonstrates its significance in maintaining cellular homeostasis and lipid metabolism. Consequently, understanding the functioning of SERINC1 can provide valuable insights into the intricate mechanisms governing cellular processes and their regulation.

Other names

LRRGT00191, otherwise known as Serine incorporator 1 or SERINC1, is commonly referred to as Tumor differentially expressed protein 1-like or TDE1L. It is also known as Tumor differentially expressed protein 2 or TDE2. Additionally, it is designated as 1500011D18Rik, AI315070, AIGP 2, KIAA1253, mKIAA1253, TMS 2, and UNQ396/PRO732 in various contexts. This protein plays an important role in several cellular processes and is involved in the regulation of cell growth and differentiation. Its expression is often altered in tumor cells, leading to increased proliferation and survival. Understanding the function of Serine incorporator 1 is crucial for developing effective cancer treatments that target this protein.

Source

Rabbit

Specificity

The SERC1 antibody is designed to recognize and bind to total SERC1 protein expressed at physiological levels within the body. This means that it is able to detect the presence of SERC1 in its native state, without interfering with its normal function. By detecting this protein, the SERC1 antibody can provide crucial insights into its biological role and help to advance our understanding of various disease processes. Thus, researchers can use the SERC1 antibody for a wide range of applications, including immunofluorescence, Western blotting, and immunoprecipitation.

Species Reactivity

Human;Mouse;Rat

Application

For Western Blotting, a dilution of 1:500~1:3000 is recommended. When it comes to Immunofluorescence/Immunocytochemistry, a dilution range of 1:100-1:500 is suggested. For ELISA assays utilizing peptides, a recommended dilution range of 1:20000-1:40000 should be used. By rephrasing the original content and rearranging the information, we can create a similar text that captures the same information.

Immunogen

A synthesized peptide derived from human SERC1

Properties

Concentration

1mg/ml

Purification

Affinity-chromatography

Clonality

Polyclonal Antibody

Stability & Storage

To maintain product stability, it is recommended to keep it stored at a temperature of -20 °C for a period of one year. Please be sure to avoid subjecting it to repeated freeze/thaw cycles, as this may impact the quality of the product.

Storage buffer

This product contains Rabbit IgG dissolved in a solution of phosphate buffered saline at pH 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. To ensure its stability, it must be stored at a temperature of -20°C, where it remains stable for 12 months from the date of receipt. For best results, please handle with care and follow the instructions provided.

Target

Background

Augments the integration of serine into sphingolipids and phosphatidylserine, thereby promoting their synthesis.

Celluar localization

The Endoplasmic Reticulum is a network of membranes within a cell that is responsible for manufacturing and packaging proteins. It is also involved in lipid synthesis and storage. The Extracellular region or secreted molecules are substances that are produced by a cell and released outside of the cell. These molecules can serve a variety of functions, such as signaling other cells or forming structural components of tissues. The Plasma Membrane is the boundary that separates the inside of a cell from the outside environment. It is selectively permeable, allowing certain molecules to pass through while blocking others. The Plasma Membrane also plays a role in cell signaling and communication.

UniPort

Q9NRX5