ACSL6 Polyclonal Antibody #abs118243

abs118243-50ul

In Stock

228

Other names

ACS2;FACL6;LACS6;LACS2;LACS5

Source

Rabbit

Species Reactivity

Human;Mouse;Rat

Application

WB 1:500 - 1:2000

Immunogen

，ACSL6（NP_001192180.1）383-622。，，。

Properties

Mouse brain, Rat brain, Mouse heart, Mouse testis, THP-1, Jurkat, Raji, 22Rv1.
The above sequence represents various samples that are commonly used in biological research. These samples include different types of cells, tissues, and organs from both mice and rats.
The mouse brain is one of the most widely studied organs in neuroscience research. It plays a crucial role in regulating various bodily functions and is a key component of the central nervous system.
Similar to the mouse brain, the rat brain is also extensively studied in neuroscience research. Rats are often used as an animal model due to their close genetic similarity to humans, making their brains an important subject of investigation.
Moving on to another organ, the mouse heart is a vital organ responsible for pumping blood throughout the body. Understanding the structure and function of the mouse heart can provide valuable insights into cardiovascular diseases and potential treatment strategies.
Next, we have the mouse testis, which is a crucial reproductive organ in male mice. Research on the mouse testis helps in understanding the processes of spermatogenesis and reproductive health.
THP-1 is a commonly used cell line derived from human monocytic leukemia. It is widely employed in immunological and hematological research, as it can be differentiated into macrophages and used to study immune responses.
Jurkat is another well-known cell line derived from human T lymphocyte leukemia. It is extensively used in immunological research to explore T cell receptor signaling, cell signaling pathways, and immune-related diseases.
Raji cells are derived from human Burkitt's lymphoma and are widely utilized in cancer research. They have been instrumental in studying various aspects of lymphoma development and potential treatment options.
Lastly, 22Rv1 is a cell line derived from human prostate cancer metastasis. It is utilized in prostate cancer research to investigate the mechanisms of tumor progression, drug resistance, and therapeutic interventions.
Overall, these different samples and cell lines play a crucial role in advancing our understanding of various biological processes, diseases, and potential treatment options.

Properties

Purification

Affinity purification

Clonality

Polyclonal Antibody

Isotype

IgG

Stability & Storage

Store at -20℃. Avoid freeze / thaw cycles.

Storage buffer

Store at -20℃. Avoid freeze / thaw cycles.
PBS with a pH of 7.3, containing 0.02% sodium azide and 50% glycerol, is a buffer solution commonly used in laboratory experiments. The addition of sodium azide acts as a preservative, while glycerol aids in maintaining the stability of the solution. This well-balanced composition ensures the optimal performance of the buffer, making it suitable for various applications. Remember to handle and store this solution properly to ensure its effectiveness and longevity.

Target

Background

This gene encodes a crucial protein that facilitates the synthesis of acyl-CoA through the utilization of fatty acids, ATP, and CoA. In this process, magnesium serves as an essential cofactor. The protein synthesized from this gene assumes a key role in the metabolism of fatty acids within the brain. Notably, when this gene undergoes translocation with the ETV6 gene, it can lead to various conditions such as myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Multiple versions of this gene have been identified, each producing distinct isoforms through alternative splicing.

Celluar localization

The membrane systems in eukaryotic cells are vital for cellular function. These include the endoplasmic reticulum membrane, microsome membrane, mitochondrion outer membrane, and peroxisome membrane. Additionally, single-pass type III membrane proteins are important constituents of these membranes. These membranes play different roles in cellular function, from protein synthesis and lipid metabolism to cellular respiration and detoxification. Understanding the structure and function of these membranes is critical for understanding cellular physiology and disease.

UniPort

Q9UKU0