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Rabbit Anti-SEMA4C Polyclonal Antibody#abs138132

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Description

Catalog-specification	Delivery time	USD price
abs138132-100ug	1-2 Weeks	301.0
abs138132-50ug	1-2 Weeks	201.0

Overview
catalog	abs138132
Other names	SEMA4C, also known as SEMACL1 or semaphorin-4C, is a protein encoded by the KIAA1739 gene. It contains a sema domain, an immunoglobulin domain (Ig), a transmembrane domain (TM), and a short cytoplasmic domain. SEMA4C is involved in axon guidance and cell migration through interactions with plexins and integrins. It is also believed to play a role in the development and progression of various cancers. UNQ5855/PRO34487 is an alternative name for SEMA4C.
Source	Rabbit
Specificity	The total SEMA4C levels in the body can be effectively identified using the SEMA4C Antibody, which specifically targets and detects endogenous SEMA4C protein. By utilizing this antibody, researchers can accurately measure the amounts of SEMA4C present in biological samples.
Species Reactivity	Human
Predictive reaction species	Rabbit;Sheep;Bovine;Horse;
Antigen	SEMA4C
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human SEMA4C.
MW	92 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, we purified the antiserum through peptide affinity chromatography. The process ensured that the resulting antiserum was highly purified and suitable for further use.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure longevity, it is recommended to store at a temperature of -20 °C for a duration of one year. It is crucial to avoid subjecting the item to repeated freeze and thaw cycles, which can compromise its quality over time.
Storage buffer	This product contains Rabbit IgG in phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20°C and has a shelf life of 12 months from the date of receipt.
Target
Background	Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Celluar localization	Extracellular region or secreted;Plasma Membrane;
UniPort	Q9C0C4