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Rabbit Anti-S100A4 Polyclonal Antibody#abs136036

Description

Catalog-specification	Delivery time	USD price
abs136036-100ug	1-2 Weeks	301.0
abs136036-50ug	1-2 Weeks	201.0

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Overview
catalog	abs136036
Description	This gene encodes a protein that belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are found in the cytoplasm and/or nucleus of various types of cells and are involved in regulating several cellular processes, such as cell cycle progression and differentiation. There are at least 13 S100 genes, located in a cluster on chromosome 1q21. This particular protein may play a role in motility, invasion, and tubulin polymerization. Studies have implicated chromosomal rearrangements and altered expression of this gene in tumor metastasis. Numerous alternatively spliced variants encoding the same protein have been identified. [RefSeq, Jul 2008]
Other names	Calcium plays a crucial role in the human body, and its importance extends to placental protein. Some of the proteins that rely on calcium include Calvasculin (also known as S100 calcium-binding protein A4), Fibroblast specific protein 1 (FSP1), and Malignant transformation suppression 1 (MTS1). These proteins are vital for various functions in the body, including suppressing malignant tumors and multidrug resistance in leukemia. Additionally, placental calcium-binding protein is essential for fetal development and growth. Another protein, Metastasin, is associated with cancer and has been found to promote the spread of cancer cells. Protein Mts1 and Protein S100 A4 are other names for the S100 calcium-binding protein A4. Overall, these proteins are crucial for maintaining optimal health and function in the human body.
Source	Rabbit
Specificity	The S100A4 Antibody is specifically designed to detect the total levels of endogenous S100A4 protein. This antibody can effectively recognize and identify the target protein and provide accurate results. By using this antibody, researchers can easily detect and measure the expression levels of S100A4 in various biological samples. Overall, the S100A4 Antibody is an essential tool for investigating the function and role of S100A4 protein in different biological processes.
Species Reactivity	Human;Mouse;Rat
Antigen	S100A4
Application	The antibody dilution ranges for WB, IHC, IF/ICC, and ELISA(peptide) are as follows: - WB: Dilution range of 1:500 to 1:2000 - IHC: Dilution range of 1:50 to 1:200 - IF/ICC: Dilution range of 1:100 to 1:500 - ELISA(peptide): Dilution range of 1:20000 to 1:40000 To ensure accurate results, it is important to dilute the antibodies within these specified ranges.
Immunogen	A synthesized peptide derived from human S100A4.
MW	12kDa
Properties
Concentration	1mg/ml
purification	The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Tissue specificity	Ubiquitously expressed.
Celluar localization	Extracellular region or secreted;Nucleus;
UniPort	P26447