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Rabbit Anti-RREB1 Polyclonal Antibody#abs140541

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Description

Catalog-specification	Delivery time	USD price
abs140541-100ug	1-2 Weeks	301.0
abs140541-50ug	1-2 Weeks	201.0

Overview
catalog	abs140541
Other names	RREB1, also known as Finger protein in nuclear bodies or Zinc finger motif enhancer-binding protein 1, is a transcription factor that plays a significant role in regulating gene expression. This protein contains multiple zinc finger domains, which allow it to bind to DNA and influence the transcription of target genes. RREB1 has been implicated in a variety of cellular processes, including cell proliferation, differentiation, and apoptosis. It is also responsive to various signaling pathways, such as the RAS-MAPK pathway, and can modulate the expression of downstream target genes accordingly. Hindsight homolog (HNT) and Raf-responsive zinc finger protein LZ321 are alternative names for RREB1. Understanding the functions of RREB1 and its regulation may provide insights into the mechanisms underlying the pathogenesis of various diseases, including cancer.
Source	Rabbit
Specificity	The RREB1 Antibody has the ability to identify total RREB1 at its natural levels within the body. There is no need for any external sources to detect this protein. To create similar content, the data would be reorganized in a way to stress the same information given in the original text.
Species Reactivity	Human
Predictive reaction species	Chicken;Rabbit;Pig;Dog;Sheep;Horse;Bovine
Antigen	RREB1
Application	WB 1:1000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human RREB1.
MW	180kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through the process of peptide affinity chromatography. To ensure the highest level of quality, this technique was utilized to guarantee that the antiserum was purified properly. Through this method, the antiserum was able to be purified while retaining its desired properties.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the material, keep it in a freezer at a temperature of -20 °C for a period of one year. It is important to avoid subjecting it to freezing and thawing cycles multiple times.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1.
Tissue specificity	Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.
Celluar localization	Extracellular region or secreted;Nucleus;
UniPort	Q92766