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Rabbit Anti-RIPK3 Polyclonal Antibody#abs136851

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Description

Catalog-specification	Delivery time	USD price
abs136851-50ug	1-2 Weeks	201.0
abs136851-100ug	1-2 Weeks	301.0

Overview
catalog	abs136851
Description	The receptor-interacting protein (RIP) family of serine/threonine protein kinases includes a unique member known as this gene's product. Unlike other RIP family members, this protein possesses a distinct C-terminal domain. Primarily found in the cytoplasm, it is capable of shuttling between the nucleus and cytoplasm based on specific nuclear localization and export signals. Functionally, it serves as a crucial component of the tumor necrosis factor (TNF) receptor-I signaling complex. Moreover, it can activate the NF-kappaB transcription factor to a limited extent and also trigger apoptosis. To summarize, this gene's product exhibits unique characteristics within the RIP family, localizes mainly in the cytoplasm, and has the ability to induce apoptosis while weakly activating NF-kappaB.
Source	Rabbit
Specificity	The RIPK3 Antibody is capable of identifying total levels of RIPK3 that occur naturally within the body. By rearranging the original content, a highly similar message has been conveyed, explaining the antibody's ability to detect endogenous RIPK3 levels.
Species Reactivity	Mouse
Antigen	RIPK3
Application	The dilution ratio for Western blot is 1:500-1:2000, for immunohistochemistry is 1:50-1:200, and for ELISA (peptide) is 1:20000-1:40000.
Immunogen	A synthesized peptide derived from Mouse RIPK3.
MW	56kDa
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography with SulfoLink™ Coupling Resin was employed to purify the antiserum. Let me provide you with a comparable version of the content by reorganizing the information.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the preservation of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting it to multiple freeze/thaw cycles.
Storage buffer	The storage condition for Rabbit IgG is at -20 °C in a solution of phosphate buffered saline with a pH of 7.4. The solution also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to note that the stability of the IgG is guaranteed for a period of 12 months from the date of receipt.
Target
UniPort	E9PZP3