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Rabbit Anti-LHX8 Polyclonal Antibody#abs136298

Description

Catalog-specification	Delivery time	USD price
abs136298-100ug	1-2 Weeks	301.0
abs136298-50ug	1-2 Weeks	201.0

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Overview
catalog	abs136298
Description	The LIM homeobox family of proteins is responsible for the differentiation and patterning of various tissues, and this particular gene encodes a member of this family. The protein contains two cysteine-rich double-zinc finger motifs, known as LIM domains, as well as a DNA-binding homeodomain. In tooth morphogenesis, oogenesis, and neuronal differentiation, this transcription factor plays a critical role. This gene is a possible candidate for cleft palate and is linked to odontoma formation. There are several transcript variants produced by alternative splicing of this gene. [RefSeq, Jan 2012]
Other names	Lhx7; Lhx8; LHX8_HUMAN; LIM homeobox protein 8; LIM Homeodomain 8; LIM homeobox protein 8; LIM/homeobox protein Lhx8; Lhx8 is a human protein encoded by the LHX8 gene. This protein belongs to the LIM-homeobox family of transcription factors and plays a role in embryonic development and cell differentiation. Lhx8 is involved in the regulation of gene expression and controls various biological processes. Its aberrant expression has been associated with certain diseases and developmental disorders. Understanding the role of Lhx8 in cellular processes may lead to new insights into disease mechanisms and potential therapeutic targets.
Source	Rabbit
Specificity	The LHX8 Antibody is capable of detecting total endogenous levels of LHX8. In other words, it can accurately identify and measure the amount of LHX8 present in a given sample. This information is important for researchers who study the function and role of LHX8 in different biological processes. By using the LHX8 Antibody, researchers can gain valuable insights into the mechanisms by which LHX8 influences cellular function and development. Overall, the LHX8 Antibody is a valuable tool for those interested in studying this important transcription factor.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Chicken;Rabbit;Pig;Dog;Bovine;Sheep;Horse;
Antigen	LHX8
Application	The dilution range for Western blot (WB) is 1:500 to 1:2000, for immunohistochemistry (IHC) is 1:50 to 1:200, and for ELISA (peptide) is 1:20000 to 1:40000. It is essential to note that the generated content will be based on the original text information.
Immunogen	A synthesized peptide derived from human LHX8.
MW	43kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. To ensure high quality, the process was carefully performed to eliminate any impurities and maintain the integrity of the antigen-antibody complex. The resulting purified antiserum can be used for a wide range of research and diagnostic applications.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Transcription factor involved in differentiation of certain neurons and mesenchymal cells.
Celluar localization	Nucleus;
UniPort	Q68G74