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Rabbit Anti-REG3G Polyclonal Antibody#abs136389

Description

Catalog-specification	Delivery time	USD price
abs136389-100ug	1-2 Weeks	301.0
abs136389-50ug	1-2 Weeks	201.0

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Overview
catalog	abs136389
Description	The REG family is a group of secretory proteins that play a vital role in the proliferation or differentiation of liver, pancreatic, gastric and intestinal cells. These proteins are classified into four subclasses, types I, II, III and IV, and all of them share the same gene structure consisting of five introns and six exons. REG family members are involved in the regulation of cell growth, cancer progression and tumorigenesis. Reg lll, also known as PAP1B, UNQ429 or pancreatitis-associated protein 1B, is a 175 amino acid secreted protein that is primarily expressed in the pancreas, with secondary expression in the testis. Reg lll has antimicrobial properties and helps in controlling bacterial proliferation, and its expression may increase during acute pancreatitis. This gene is located on human chromosome 2, which contains over 1,400 genes, making up 8% of the human genome.
Other names	Pancreatitis-associated protein 1B, also known as PAP IB, PAP-1B, PAP1B, or PAPIB, is a protein coded by the REG3G gene in humans. REG3G is also known as Reg III-gamma, REG-3-gamma, or Regenerating islet-derived protein 3-gamma. This protein plays a role in the pathogenesis of pancreatitis, a condition characterized by inflammation of the pancreas. Additionally, REG3G is involved in the regulation of cell growth and differentiation. The UNQ429 protein is also closely related to REG3G and is currently being studied for its potential therapeutic uses. Overall, the study of REG3G and its related proteins provides insights into the molecular mechanisms underlying pancreatic diseases and cell growth regulation.
Source	Rabbit
Specificity	The REG3G Antibody is capable of detecting the total amount of REG3G present in the organism. The levels of REG3G detected would be from the endogenous sources. By rephrasing this information, we could say that the REG3G Antibody has the ability to identify the entirety of REG3G levels that are naturally occurring within the organism.
Species Reactivity	Human;Mouse;Rat
Antigen	REG3G
Application	，：（WB），1:5001:2000。（IHC），1:501:200。（ELISA），1:200001:40000。。，。
Immunogen	A synthesized peptide derived from mouseREG3G.
MW	19kDa
Properties
Concentration	1mg/ml
purification	The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Tissue specificity	Predominantly expressed in the small intestine, including Paneth cells (at protein level). Hardly detectable in the colon (at protein level). Highly expressed in the lung epithelium during methicillin-resistant S.aureus infection (at protein level). Skin injury increases its epidermal expression. Also expressed in the pancreas.
UniPort	O09049