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Rabbit Anti-INTS2 Polyclonal Antibody#abs140452

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Description

Catalog-specification	Delivery time	USD price
abs140452-100ug	1-2 Weeks	301.0
abs140452-50ug	1-2 Weeks	201.0

Overview
catalog	abs140452
Other names	INT2; Integrator complex subunit 2; KIAA1287;
Source	Rabbit
Specificity	The endogenous levels of total INTS2 can be detected by the INTS2 Antibody. Its ability to detect endogenous levels of total INTS2 makes it a valuable tool in research.
Species Reactivity	Human;Mouse
Antigen	INTS2
Application	The recommended dilution for WB is 1:1000, while the suggested dilution range for IF/ICC is between 1:100 to 1:500. For ELISA with peptides, the recommended dilution range is 1:20000 to 1:40000. It is important to follow these dilution recommendations to ensure optimal results in your experiments.
Immunogen	A synthesized peptide derived from human INTS2.
MW	140kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was carried out through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain its quality, it is recommended to store the product at -20 °C for a year. Please make sure to avoid subjecting it to repeated freeze/thaw cycles.
Storage buffer	This product contains rabbit IgG in a solution of phosphate buffered saline at a pH of 7.4, with 150mM of NaCl, and 0.02% sodium azide. It has been mixed with 50% glycerol and should be stored at a temperature of -20 °C for optimal stability. This formulation has a shelf life of 12 months from the date of receipt, making it a reliable choice for long-term storage and use. So if you're looking for a reliable source of rabbit IgG for your research needs, this product is definitely worth considering!
Target
Background	The Integrator complex, which is involved in the transcription and processing of small nuclear RNAs U1 and U2, is made up of various components including INT. This complex is responsible for interacting with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and targeting the U1 and U2 snRNA genes. It is believed that INT also plays a role in recruiting cytoplasmic dynein to the nuclear envelope. This indicates that INT has multiple functions within the cell and its involvement in various cellular processes makes it an important component of the Integrator complex.
Celluar localization	Nucleus;
UniPort	Q9H0H0