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Rabbit Anti-Recoverin Polyclonal Antibody#abs133462

Please note that the price mentioned above is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent. Western blot analysis of extracts from NIH-3T3 cells, using Recoverin antibody. This product is for research use only, not for use in diagnostic...

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Description

Catalog-specification	Delivery time	USD price
abs133462-100ug	1-2 Weeks	301.0
abs133462-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent.

Overview
catalog	abs133462
Other names	Protein CAR, also known as Recoverin, is a 23 kDa photoreceptor cell-specific protein that is associated with cancer-associated retinopathy. Its primary function is not fully understood, but it plays a crucial role in the regulation of calcium homeostasis and signaling in the retina. CAR protein, also referred to as p26 or S-modulin, is predominantly expressed in photoreceptor cells and has been implicated in the development and progression of various types of cancer. Studies have shown that alterations in CAR protein expression and function are associated with the pathogenesis of cancer-associated retinopathy. As a cancer-associated retinopathy protein, CAR is believed to participate in the control of cell proliferation, survival, and differentiation in retinal tissues. The identification and characterization of CAR protein have led to a better understanding of the molecular mechanisms underlying cancer-associated retinopathy and have provided new insights into potential therapeutic strategies for this condition.
Source	Rabbit
Specificity	The Recoverin Antibody is designed to recognize and measure the natural levels of total Recoverin in the body. Its purpose is to detect the endogenous presence of this protein. To achieve this, the antibody has been specifically developed to bind to Recoverin, allowing researchers to assess its total amount accurately. This tool is widely used in scientific studies and can provide valuable insights into the role of Recoverin in various physiological processes.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Sheep;Dog;Bovine;Horse
Antigen	Recoverin
Application	For Western Blotting, the recommended dilution range is 1:500 to 1:1000, while for Immunofluorescence/Immunocytochemistry, it is recommended to use a dilution of 1:100 to 1:500. For ELISA using peptide, the recommended dilution range is 1:20000 to 1:40000. These dilutions are important for obtaining accurate and reliable results. It is important to follow the recommended dilution range and optimize the dilution for each assay to ensure the best possible results. The dilution range may vary depending on the specific experiment and antibody used. Therefore, it is recommended to validate the dilution range for each assay to ensure optimal performance.
Immunogen	A synthesized peptide.
MW	23 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized in the peptide affinity chromatography process to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the preservation of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is important to prevent the product from undergoing multiple freeze/thaw cycles.
Storage buffer	This solution contains Rabbit IgG in phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage at -20 °C is recommended, and it is stable for up to 12 months from the date of receipt. Please note that this information should be used as a reference only and does not constitute medical advice. It is important to consult with a healthcare professional prior to use.
Target
Background	Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.
Tissue specificity	Retina and pineal gland.
UniPort	P35243