Rabbit Anti-PRIM1 Polyclonal Antibody#abs141079

Rabbit Anti-PRIM1 Polyclonal Antibody#abs141079

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Description

Catalog-specificationDelivery timeUSD price

abs141079-100ug

1-2 Weeks

301.0

abs141079-50ug

1-2 Weeks

201.0

Important: Please note that the price mentioned above is only for your reference. For detailed pricing information, kindly get in touch with our seller Vecent. To provide you with a different approach to generating content, I will now speak in a manner distinct from how it would be generated by ChapGPT.


Overview

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abs141079
Other namesDNA primase is an important enzyme involved in DNA replication. It is composed of two subunits: a 49 kDa subunit and a small subunit. In humans, the 49 kDa subunit is encoded by the gene MGC107288, also known as MGC109113 or p49. The protein product of this gene is referred to as PRI1_HUMAN or PRIM1.
The DNA primase 49 kDa subunit is responsible for synthesizing short RNA fragments, known as primers, that are necessary for initiating DNA replication. These primers provide a starting point for DNA polymerase to add nucleotides and extend the DNA strand during replication. The small subunit of DNA primase helps stabilize the interaction between the enzyme and the DNA template.
The gene MGC107288, also known as MGC109113 or p49, encodes the 49 kDa subunit of DNA primase. This gene is highly conserved across species and plays a crucial role in DNA replication. The protein product of MGC107288, known as PRI1_HUMAN or PRIM1, is essential for the accurate and efficient replication of DNA.
In summary, DNA primase is a crucial enzyme involved in DNA replication, and its 49 kDa subunit plays a vital role in synthesizing primers. The gene MGC107288, also known as MGC109113 or p49, encodes this subunit, and its protein product is referred to as PRI1_HUMAN or PRIM1.
SourceRabbit
SpecificityThe PRIM1 Antibody has the ability to recognize the total PRIM1 present in the cells naturally. To produce a similar content by rearranging the original text, we can say that the total endogenous levels of PRIM1 can be detected using the PRIM1 Antibody.
Species ReactivityHuman;Mouse;Rat
Predictive reaction speciesBovine;Sheep;Rabbit
AntigenPRIM1
ApplicationTo use the antibody in western blotting, dilute it at a ratio of 1:500 to 1:1000. For IF/ICC applications, dilute the antibody at a range of 1:100 to 1:500. ELISA assays using peptide technology require a dilution of 1:20000 to 1:40000. It is important to adhere to these dilution ranges for optimal antibody performance.
ImmunogenA synthesized peptide.
MW50 KD
Properties

Concentration

1mg/ml

purificationSulfoLink™ Coupling Resin was employed for peptide affinity chromatography in order to purify the antiserum.
ClonalityPolyclonal Antibody
Stability & StorageTo ensure optimal preservation, it is recommended that the item is kept at a temperature of -20 °C for up to one year. Please take care to avoid exposing the item to repeated cycles of freezing and thawing.
Storage bufferThe Rabbit IgG is stored in phosphate buffered saline at a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be kept at a temperature of -20 °C for optimal stability. This product has a shelf life of 12 months starting from the date of receipt.

Target

Background

DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

Celluar localizationNucleus;
UniPortP49642


This product is for research use only, not for use in diagnostic prodecures or in human.


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