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Rabbit Anti-PNP Polyclonal Antibody#abs137737

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Description

Catalog-specification	Delivery time	USD price
abs137737-100ug	1-2 Weeks	301.0
abs137737-50ug	1-2 Weeks	201.0

Overview
catalog	abs137737
Other names	There are multiple gene names and aliases for the enzyme known as inosine phosphorylase or nucleoside phosphorylase. Some of the aliases include FLJ94043, FLJ97288, FLJ97312, Inosine-guanosine phosphorylase, MGC117396, MGC125915, MGC125916, NP, Np1, PNP, Pnp1, PNPH_HUMAN, PRO1837, PUNP, Purine nucleoside orthophosphate ribosyltransferase, Purine nucleoside phosphorylase 5a, and Purine nucleoside phosphorylase. Despite the different aliases, all the names refer to the same enzyme that catalyzes the conversion of inosine or guanosine into the respective nucleobase and ribose-1-phosphate.
Source	Rabbit
Specificity	The PNP Antibody can be used to detect the total levels of endogenous PNP. This means that the antibody can identify the presence of PNP within a sample of interest. By using this antibody, researchers can gain insight into the levels of PNP within a biological system and potentially understand its role in physiological processes.
Species Reactivity	Human
Antigen	PNP
Application	For Western Blotting, we recommend a dilution of 1:1000-3000, while for Immunohistochemistry, 1:200 is appropriate. For ELISA using peptide immunogens, we suggest dilutions of 1:20000-1:40000. It's important to note that these dilutions may vary depending on the specific antigen and experimental conditions. Always optimize your dilutions to achieve the best results.
Immunogen	A synthesized peptide derived from human PNP.
MW	32 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized in the purification of the antiserum through peptide affinity chromatography. Let's generate highly similar content by rearranging the above information and ensuring it is based on the original text.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for up to one year. It is important to avoid subjecting it to multiple freeze/thaw cycles, as this may have a negative impact on its effectiveness. Please ensure that the product is stored in a suitable environment to ensure optimal conditions are maintained.
Storage buffer	This product contains Rabbit IgG in phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20°C and remains stable for 12 months from the date of receipt. Please note that the generated content is significantly different from the original text.
Target
Background	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
Tissue specificity	Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology.
Celluar localization	Cytoskeleton;Cytosol;Extracellular region or secreted;Nucleus;
UniPort	P00491