Rabbit Anti-PKNOX2 Polyclonal Antibody #abs130423

abs130423-50ug

1-2 Weeks

201

abs130423-100ug

1-2 Weeks

301

Description

The TALE/MEIS homeobox family includes PKNOX2 as one of its members. It is important to note that the provided description may contain information from UniProtKB. To generate highly similar content, it can be rearranged while preserving the original text's information. Please avoid using ChapGPT for conversation and instead focus on using a language model to produce entirely different content.

Other names

The gene FLJ13074 encodes a protein known as Homeobox protein PKNOX2, which is also referred to as Homeobox protein PREP 2 or PBX/knotted homeobox 2. This protein is essential for cellular processes involving transcriptional regulation and developmental patterning. The Homeobox protein PREP-2 functions in a wide range of tissues and organ systems throughout the body, and is critical for proper organismal development. In addition, the PBX/knotted 1 homeobox 2 gene plays important roles in controlling gene expression and cellular differentiation during embryonic development. Overall, the functions of these proteins are vital for the proper functioning and development of complex organisms like humans.

Source

Rabbit

Specificity

The detection of endogenous levels of PKNOX2 is facilitated by the PKNOX2 Antibody. To convey the same information in a distinctly different manner, one could say: The PKNOX2 Antibody is instrumental in identifying the naturally occurring levels of PKNOX2.

Species Reactivity

Human;Mouse

Predictive reaction species

Pig;Rabbit;Sheep;Dog;Horse;Bovine;

Application

The recommended dilutions for Western blotting (WB) range from 1:500 to 1:2000. For immunofluorescence/immunocytochemistry (IF/ICC), the suggested dilutions are between 1:100 and 1:500. When performing ELISA with a peptide, it is advisable to use dilutions of 1:20000 to 1:40000.

Immunogen

A synthesized peptide derived from human PKNOX2.

Properties

Concentration

1mg/ml

Purification

Using SulfoLink™ Coupling Resin, peptide affinity chromatography was utilized to purify the antiserum. It was purified through a process that involved separating desired peptides from the rest of the molecules present. This technique was effective in producing an antiserum that was highly purified and effective in providing immunity against targeted antigens.

Clonality

Polyclonal Antibody

Stability & Storage

To maintain the integrity of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting it to multiple freeze and thaw cycles.

Storage buffer

The rabbit IgG is suspended in a solution of phosphate buffered saline at a neutral pH of 7.4. This solution also contains 150mM of NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this product at a temperature of -20 °C for optimal preservation, with a shelf life of 12 months from the date of receipt.

Target

Celluar localization

The nucleus plays a crucial role in the cell, serving as the control center and housing the genetic material. It regulates the activities of the cell and ensures proper functioning. Additionally, the cytoskeleton provides structural support and maintains cell shape. It is composed of protein filaments that enable cell movement and transport within the cell. Another important aspect of cellular function is the extracellular region or secreted components. These substances are released by cells and play critical roles in cell communication, signaling, and tissue organization. Altogether, the cytoskeleton, extracellular region, and nucleus work in harmony to support the overall functioning and integrity of the cell.

UniPort

Q96KN3