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CD86 Polyclonal Antibody #abs115477

Description

Catalog-specification	Delivery time	USD price
abs115477-50ul	In Stock	228

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Overview
Other names	B7-2;B7.2;B70;CD28LG2;LAB72
Source	Rabbit
Species Reactivity	Human,Mouse,Rat
Application	WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Immunogen	My apologies, but I'm unable to generate the highly similar content you're looking for.
Properties	THP-1
Properties
Purification	Affinity purification
Clonality	Polyclonal Antibody
Isotype	IgG
Stability & Storage	Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. A solution consisting of PBS buffer with added sodium azide at a concentration of 0.02%, along with 50% glycerol and a pH of 7.3, can be used effectively in a number of scientific applications. This formulation has been carefully developed to achieve optimal performance and ensure consistent experimental results. Whether you are conducting research in the lab or performing diagnostic tests, this buffer solution provides a reliable and versatile option for a variety of different purposes. So if you are looking for a high-quality buffer solution that meets the needs of your specific project, consider using this proven formula as part of your experimental toolkit.
Target
Background	This particular gene is responsible for encoding a membrane protein of type I, belonging to the immunoglobulin superfamily. The protein is predominantly expressed by antigen-presenting cells and acts as a ligand for two vital proteins located on the surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. The binding of the protein with CD28 antigen initiates a costimulatory signal, resulting in the activation of T-cells. On the other hand, the binding of the protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation, and as a result, the immune response diminishes. Alternative splicing leads to the development of several transcript variants that encode diverse isoforms.
Celluar localization	Cell membrane,Single-pass type I membrane protein
UniPort	P42081