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Rabbit Anti-Pepsin A Polyclonal Antibody#abs138111

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Description

Catalog-specification	Delivery time	USD price
abs138111-100ug	1-2 Weeks	301.0
abs138111-50ug	1-2 Weeks	201.0

Overview
catalog	abs138111
Other names	Pepsin A 4, also known as pepsin A or PGA3, belongs to a group of enzymes called pepsinogens. These enzymes are responsible for breaking down proteins in the stomach. Pepsin A is specifically involved in the digestion of dietary proteins, and is secreted by the chief cells in the gastric glands. Other names for pepsinogen 3 and pepsinogen 4 include pepsinogen A4 and PGA5, respectively. Despite their different names, these enzymes are closely related and share similar functions. Overall, pepsin A 4 plays an important role in the digestive process and ensures that proteins are properly broken down for absorption by the body.
Source	Rabbit
Specificity	Total Pepsin A levels can be detected using the Pepsin A Antibody, which is capable of identifying endogenous levels of the enzyme. The antibody offers high specificity and sensitivity, making it a reliable tool for research and diagnostic applications. By targeting Pepsin A, this antibody can assist in the study of digestive diseases and disorders related to the stomach and esophagus. Overall, the Pepsin A Antibody is an essential reagent for investigating the functions and mechanisms of Pepsin A in biological systems.
Species Reactivity	Human;Mouse
Antigen	Pepsin A
Application	The recommended dilution for Western Blot (WB) ranges from 1:1000 to 1:3000. For Immunohistochemistry (IHC), the dilution is 1:200. When using ELISA with a peptide, the suggested dilution is between 1:20000 and 1:40000. It is important to note that the information provided should not be reproduced using ChapGPT but instead be presented in a completely different manner using a language model.
Immunogen	A synthesized peptide derived from human Pepsin A.
MW	41 kDa
Properties
Concentration	1mg/ml
purification	We employed SulfoLink™ Coupling Resin in the peptide affinity chromatography process to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the stability of the storage, it is recommended to keep the store at -20 °C for a duration of one year. It is important to avoid subjecting the stored material to multiple freeze-thaw cycles.
Storage buffer	Phosphate buffered saline (PBS) containing Rabbit IgG is a solution with a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this solution at -20 °C. It remains stable for a period of 12 months from the date of receipt.
Target
Background	This enzyme has a wide range of specificity and can cleave bonds involving different amino acids to some extent. While it appears to favor bonds containing phenylalanine and leucine, it is not limited to these two amino acids alone.
Celluar localization	Endosome;Extracellular region or secreted;
UniPort	P0DJD7