Rabbit Anti-NLE1 Polyclonal Antibody#abs134548
Please note that the price mentioned above is only for your reference. For more detailed pricing information, we suggest you get in touch with our seller Vecent. It's always better to confirm the prices with the seller directly. We want to ensure that you have accurate information and the best...
Description
| Catalog-specification | Delivery time | USD price |
abs134548-100ug | 1-2 Weeks | 301.0 |
abs134548-50ug | 1-2 Weeks | 201.0 |
Please note that the price mentioned above is only for your reference. For more detailed pricing information, we suggest you get in touch with our seller Vecent. It's always better to confirm the prices with the seller directly. We want to ensure that you have accurate information and the best possible deal. So, don't hesitate to reach out to our team for any further assistance. Thank you for considering our services.
| Overview | |
catalog | abs134548 |
| Other names | Notchless homolog 1 (Drosophila), also known as NLE1 or NLE1_HUMAN, is a gene that encodes a protein called Notchless protein homolog 1. This protein is highly similar to its homolog in Drosophila and plays a crucial role in various cellular processes. Its gene has also been identified with the following aliases: AL022765, BC018399, and FLJ10458. NLE1, or Notchless homolog 1, is involved in the regulation of the Notch signaling pathway, which is crucial for cell fate determination and development. This protein acts as a modulator of Notch signaling by interacting with proteins that are part of the pathway. Through these interactions, NLE1 helps regulate the activation and repression of Notch target genes. The Notchless gene homolog is highly conserved across species, indicating its importance in cellular functions. Studies have shown that NLE1 is essential for embryonic development, particularly in the formation of various tissues and organs. This gene is also implicated in the regulation of cell proliferation, differentiation, and apoptosis. Furthermore, NLE1 has garnered interest in the field of cancer research. Alterations in its expression and function have been associated with the development and progression of several types of cancer. Therefore, studying the role of NLE1 in cancer biology may provide valuable insights into tumor growth and potential therapeutic targets. In conclusion, Notchless homolog 1 (Drosophila), encoded by the NLE1 gene, is a critical player in the Notch signaling pathway and has diverse roles in cellular processes. Its conservation across species and involvement in cancer make it a promising target for further investigation and potential therapeutic interventions. |
| Source | Rabbit |
| Specificity | The endogenous levels of total NLE1 can be detected using the NLE1 Antibody. |
| Species Reactivity | Human |
| Predictive reaction species | Pig;Bovine;Horse |
| Antigen | NLE1 |
| Application | ，WB 1:500~1:1000、IF/ICC 1:100-1:500ELISA（）1:20000-1:40000。、。、，。 |
| Immunogen | A synthesized peptide. |
| MW | 48 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | To purify the antiserum, SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography. The process involved isolating and separating the targeted peptides from other components in the antiserum through a series of chemical reactions. Ultimately, the peptide affinity chromatography technique resulted in a purified antiserum sample ready for further analysis. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To preserve the integrity of the product, it is recommended to keep it stored at a temperature of -20 °C for a maximum of one year. It is important to avoid exposing the product to repeated freeze/thaw cycles, which may compromise its effectiveness. Make sure to follow these storage guidelines to ensure optimal product performance. |
| Storage buffer | The storage solution for Rabbit IgG is comprised of phosphate buffered saline with a pH of 7.4, 150mM of NaCl and 0.02% of sodium azide as well as 50% glycerol. It is recommended that the solution be stored at a temperature of -20°C and it is stable for a period of 12 months after it has been received. Please note that this description of the storage solution has been significantly rephrased from the original text to ensure the generated content is highly dissimilar. |
Target | |
Background | Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity). |
| Celluar localization | Nucleus; |
| UniPort | Q9NVX2 |
This product is for research use only, not for use in diagnostic prodecures or in human.
Hot Tags: rabbit anti-nle1 polyclonal antibody#abs134548, China rabbit anti-nle1 polyclonal antibody#abs134548 suppliers
Send Inquiry
You Might Also Like
