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Rabbit Anti-P2RY4 Polyclonal Antibody#abs135438

Please note that the price provided above is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. Western blot analysis of extracts from HeLa cells, using P2RY4 antibody. This product is for research use only, not for use in...

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Description

Catalog-specification	Delivery time	USD price
abs135438-50ug	1-2 Weeks	201.0
abs135438-100ug	1-2 Weeks	301.0

Please note that the price provided above is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.

Overview
catalog	abs135438
Other names	The NRU, also known as the nucleotide receptor uridine, is a key component in the P2P signaling pathway. This pathway is activated by the P2RY4 receptor, also known as P2Y purinoceptor 4 or P2Y4R. The P2RY4 receptor is a member of the pyrimidinergic receptor family, which are all G protein-coupled receptors. The UNR, or uridine nucleotide receptor, is another name for the P2RY4 receptor. This receptor is involved in various physiological processes, including inflammation, cell proliferation, and cell differentiation. It is also involved in modulating neurotransmission in the central nervous system. Overall, the P2RY4 receptor plays an important role in the regulation of cellular functions and is a potential target for therapeutic intervention in various diseases. Research is ongoing to further understand the specific mechanisms that underlie its function and potential clinical applications.
Source	Rabbit
Specificity	The presence of total P2RY4 can be identified using the P2RY4 antibody, which is capable of detecting endogenous levels of this protein.
Species Reactivity	Human;Mouse;Rat
Antigen	P2RY4
Application	。，WB1:5001:1000，Western Blot；IF/ICC，1:1001:500；，ELISA(peptide)，1:200001:40000。，、。
Immunogen	A synthesized peptide.
MW	41 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography for purification. To obtain a highly pure and potent antiserum, this advanced method was employed which utilizes the resin's unique ability to bind only to the desired peptides and separate them from other unwanted substances. Thus, the resulting antiserum was of exceptional quality and was ready for use in various scientific applications.
Clonality	Polyclonal Antibody
Stability & Storage	Ensure that the storage temperature is maintained at -20 °C for a duration of one year without subjecting to freeze/thaw cycles.
Storage buffer	The storage condition for Rabbit IgG is at -20 °C in phosphate-buffered saline with a pH of 7.4. It is formulated with 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This product remains stable for a period of 12 months starting from the date of receipt.
Target
Background	Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP.
Tissue specificity	Pancreas.
Posttranslational modification	Phosphorylation of Ser-333 and Ser-334 is a key step in agonist-dependent desensitization and loss of surface P2RY4. This phosphorylation does not involve PKC, nor other calcium activated kinases.
Celluar localization	Plasma Membrane;
UniPort	P51582