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Rabbit Anti-MGST1 Polyclonal Antibody#abs141240

Please note that the price mentioned above is only for your reference. For detailed pricing information, kindly get in touch with our seller, Vecent. Western blot analysis of extracts from HeLa cells, using MGST1 antibody. This product is for research use only, not for use in diagnostic...

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Description

Catalog-specification	Delivery time	USD price
abs141240-100ug	1-2 Weeks	301.0
abs141240-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. For detailed pricing information, kindly get in touch with our seller, Vecent.

Overview
catalog	abs141240
Other names	Glutathione S transferase 12, also known as GST12 or MGST1, is an essential enzyme for the detoxification of harmful substances in the body. It is a member of the microsomal glutathione S-transferase family and plays a crucial role in protecting cells from oxidative stress. In humans, MGST1 is highly expressed in tissues such as the liver, lung, and stomach, where it helps to eliminate toxic compounds that can contribute to the development of cancer and other diseases. MGST1 is also involved in the metabolism of drugs and foreign substances, making it an important target for drug discovery research. Overall, the functions of MGST1 make it a critical component of the body's defense systems against harmful agents, and scientists continue to study its role in health and disease.
Source	Rabbit
Specificity	The MGST1 Antibody is capable of detecting total levels of endogenous MGST1 in the body. To create another version of this sentence using the same information, one could say: The total amounts of endogenous MGST1 within the body can be detected with the MGST1 Antibody.
Species Reactivity	Human
Predictive reaction species	Sheep;Bovine;Dog;Horse;
Antigen	MGST1
Application	For Western blotting, a dilution ratio of 1:500 to 1:1000 is recommended, while IF/ICC staining should be performed using a dilution of 1:100 to 1:500. When performing ELISA with a peptide, a dilution of 1:20000 to 1:40000 is suggested. It is important to follow these recommended dilutions to ensure accurate and reliable results in your experiments.
Immunogen	A synthesized peptide.
MW	18 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality, store at -20 °C for one year, and make sure to prevent frequent freezing and thawing cycles.
Storage buffer	This is a description of Rabbit IgG, which is stored in phosphate buffered saline (pH 7.4) with 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20 °C and has a shelf life of 12 months from the date of receipt.
Target
Background	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity.
Tissue specificity	Highly expressed in liver.
Posttranslational modification	Peroxynitrite induces nitration at Tyr-93 which activates the enzyme.
Celluar localization	Endoplasmic reticulum;Lysosome;Mitochondrion;Nucleus;Peroxisome;Plasma Membrane;
UniPort	P10620