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Rabbit Anti-Osterix Polyclonal Antibody#abs137208

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Description

Catalog-specification	Delivery time	USD price
abs137208-100ug	1-2 Weeks	301.0
abs137208-50ug	1-2 Weeks	201.0

Overview
catalog	abs137208
Other names	Osterix, also known as Sp7 or Osx, is a zinc finger protein and a transcription factor. It plays a crucial role in bone development and is encoded by the MGC126598 gene in humans. Transcription factor Sp7, or SP7_HUMAN, is responsible for regulating the expression of several genes involved in osteoblast differentiation and bone formation. Its involvement in skeletal development makes it an important player in maintaining bone health.
Source	Rabbit
Specificity	The Osterix Antibody is useful for detecting the total levels of endogenous Osterix. You can create an equivalent statement by rearranging the information in the original text.
Species Reactivity	Human;Mouse;Rat
Antigen	Osterix
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human Osterix.
MW	46 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed for peptide affinity chromatography to purify the antiserum. Please generate a content with high similarity by rearranging the provided information, while maintaining its original meaning.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is recommended to store the product at a temperature of -20°C for a period of one year. To avoid any potential damage, it is important to avoid exposing the product to repeated freeze and thaw cycles. By following these guidelines, you can preserve the quality and integrity of the product for an extended period of time.
Storage buffer	The Rabbit IgG solution in phosphate buffered saline (pH 7.4) with 150mM NaCl, 0.02% sodium azide, and 50% glycerol is recommended for storage at -20 °C. The solution is guaranteed to remain stable for up to 12 months from the date of receipt. It's important to ensure that the storage conditions are maintained to guarantee optimal performance and stability of the product.
Target
Background	A crucial factor for the differentiation of osteoblasts is the transcriptional activator. This activator is known to bind to consensus sequences such as SP1 and EKLF, as well as other sequences rich in G/C content. The binding of this activator to these sequences plays a vital role in initiating and promoting osteoblast differentiation.
Tissue specificity	Restricted to bone-derived cell.
Posttranslational modification	Ubiquitination at leads to proteasomal degradation. SP7 is a short-live protein with an endogenous half-life of approximately 12 hours.
Celluar localization	Nucleus;
UniPort	Q8TDD2