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Rabbit Anti-Oct-6 Polyclonal Antibody#abs140490

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Description

Catalog-specification	Delivery time	USD price
abs140490-100ug	1-2 Weeks	301.0
abs140490-50ug	1-2 Weeks	201.0

Overview
catalog	abs140490
Other names	Oct-6, also known as Octamer-binding protein 6 or Octamer-binding transcription factor 6, is a transcription factor belonging to the POU class 3 homeobox family. It is encoded by the gene PO3F1_HUMAN and is also referred to as POU domain transcription factor SCIP or POU domain class 3 transcription factor 1. Oct-6 plays a crucial role in controlling gene expression and regulating various cellular processes. Its function is essential for the development and maintenance of the nervous system and is involved in the differentiation of oligodendrocytes. Through its DNA binding domain, Oct-6 interacts with specific target genes, activating or repressing their transcription. This transcription factor holds promising implications in various biological processes and may serve as a potential therapeutic target in certain diseases.
Source	Rabbit
Specificity	The Oct-6 Antibody is capable of detecting the naturally occurring levels of total Oct-6 within the body. The antibody is designed to recognize and bind to Oct-6, allowing for accurate measurements and detection of this protein. This is a valuable tool in scientific research, as understanding the levels of Oct-6 within different tissues can provide insights into its role in various biological processes.
Species Reactivity	Human;Mouse
Predictive reaction species	Zebrafish;Rabbit;Pig;Dog;Horse;Bovine;
Antigen	OCT6
Application	The recommended dilutions for this particular antibody are WB 1:1000, IF/ICC 1:100-1:500, and ELISA(peptide) 1:20000-1:40000. It is important to note that appropriate dilutions may vary depending on the specific application and experimental conditions. When using this antibody in Western blotting, we suggest starting with a 1:1000 dilution and optimizing from there. For immunofluorescence or immunocytochemistry, a dilution range of 1:100-1:500 is typically appropriate. In ELISA using peptide, a dilution range of 1:20000-1:40000 should be sufficient for effective detection. It is always recommended to perform a titration experiment to determine the optimal dilution for your particular experimental setup.
Immunogen	A synthesized peptide derived from human Oct-6.
MW	45kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. A highly refined product was achieved through this process.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain its integrity, keep the product stored at a temperature of -20 °C for a period of one year, and be sure to avoid subjecting it to repeated freeze/thaw cycles.
Storage buffer	This product contains rabbit IgG dissolved in phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store the product at a temperature of -20°C for optimal stability, and it is guaranteed to remain stable for a period of 12 months from the date of receipt.
Target
Background	Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Thought to be involved in early embryogenesis and neurogenesis.
Tissue specificity	Expressed in embryonal stem cells and in the developing brain.
Celluar localization	Nucleus;
UniPort	Q03052